Antibody Catalyzed Cationic Cyclization

Two major goals for the design of new catalysts are the facilitation of chemical transformations and control of product outcome. An antibody has been induced that efficiently catalyzes a cationic cyclization in which an acyclic olefinic sulfonate ester substrate is converted almost exclusively (98 p...

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Veröffentlicht in:	Science (American Association for the Advancement of Science) 1994-05, Vol.264 (5163), p.1289-1293
Hauptverfasser:	Li, Tingyu, Janda, Kim D., Ashley, Jon A., Lerner, Richard A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkenes Animals Antibodies Antibodies, Catalytic - chemistry Antibodies, Monoclonal - chemistry Biological and medical sciences Biotechnology Catalysis Catalysts Cations - chemistry Chromatography, Gas Cyclization Enzyme engineering Esters Fundamental and applied biological sciences. Psychology Haptens Kinetics Logical Thinking Methods. Procedures. Technologies Mice Miscellaneous Organic chemistry Organosilicon Compounds - chemistry Reaction mechanisms Research Article Silanes Silicon Sulfanilic Acids - chemistry Sulfonates
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