CT and MR distinction of adenomas and nonadenomas of the adrenal gland
Because the distinction between adenomas and nonadenomas of the adrenal gland is essential, we investigated which of the following parameters--size, CT attenuation values, MRI signal intensity ratios on T1- and T2-weighted sequences, calculated T2 relaxation times, or T2 relaxation time ratios--prov...
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| Veröffentlicht in: | Journal of computer assisted tomography 1994-05, Vol.18 (3), p.432-438 |
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| container_title | Journal of computer assisted tomography |
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| creator | VAN ERKEL, A. R VAN GILS, A. P. G LEQUIN, M KRUITWAGEN, C BLOEM, J. L FALKE, T. H. M |
| description | Because the distinction between adenomas and nonadenomas of the adrenal gland is essential, we investigated which of the following parameters--size, CT attenuation values, MRI signal intensity ratios on T1- and T2-weighted sequences, calculated T2 relaxation times, or T2 relaxation time ratios--provides better discrimination.
We compared these parameters in 44 adrenal masses of 37 patients by means of the Student t test and receiver operating characteristics (ROC) analyses.
Only size, CT attenuation values, and signal intensity ratios on T2-weighted MR images of adenomas showed a significant difference from those of nonadenomas. With use of ROC analysis, CT demonstrated a significantly larger area under the curve compared to size and T2 signal intensity ratios, indicating superior performance.
We found attenuation values on non-contrast-enhanced CT to be the best method in discriminating adrenal adenomas from nonadenomas. Adrenal masses with CT attenuation values below 15 HU warrant no further investigations. |
| doi_str_mv | 10.1097/00004728-199405000-00017 |
| format | Article |
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We compared these parameters in 44 adrenal masses of 37 patients by means of the Student t test and receiver operating characteristics (ROC) analyses.
Only size, CT attenuation values, and signal intensity ratios on T2-weighted MR images of adenomas showed a significant difference from those of nonadenomas. With use of ROC analysis, CT demonstrated a significantly larger area under the curve compared to size and T2 signal intensity ratios, indicating superior performance.
We found attenuation values on non-contrast-enhanced CT to be the best method in discriminating adrenal adenomas from nonadenomas. Adrenal masses with CT attenuation values below 15 HU warrant no further investigations.</description><identifier>ISSN: 0363-8715</identifier><identifier>EISSN: 1532-3145</identifier><identifier>DOI: 10.1097/00004728-199405000-00017</identifier><identifier>PMID: 8188912</identifier><identifier>CODEN: JCATD5</identifier><language>eng</language><publisher>Hagerstown, MD: Lippincott</publisher><subject>Adenoma - diagnosis ; Adenoma - diagnostic imaging ; Adrenal Gland Neoplasms - diagnosis ; Adrenal Gland Neoplasms - diagnostic imaging ; Adrenal Glands - diagnostic imaging ; Adrenal Glands - pathology ; Adrenals. Adrenal axis. Renin-angiotensin system (diseases) ; Adrenocortical Adenoma - diagnosis ; Adrenocortical Adenoma - diagnostic imaging ; Adult ; Aged ; Biological and medical sciences ; Diagnosis, Differential ; Endocrinopathies ; Female ; Humans ; Magnetic Resonance Imaging ; Male ; Medical sciences ; Middle Aged ; Non tumoral diseases. Target tissue resistance. Benign neoplasms ; ROC Curve ; Tomography, X-Ray Computed</subject><ispartof>Journal of computer assisted tomography, 1994-05, Vol.18 (3), p.432-438</ispartof><rights>1994 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c405t-58b9a89fa06c16f8e3e5fe24cd690542a660b85c9a55b2b8da1346ff59a6a56e3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=4078346$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/8188912$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>VAN ERKEL, A. R</creatorcontrib><creatorcontrib>VAN GILS, A. P. G</creatorcontrib><creatorcontrib>LEQUIN, M</creatorcontrib><creatorcontrib>KRUITWAGEN, C</creatorcontrib><creatorcontrib>BLOEM, J. L</creatorcontrib><creatorcontrib>FALKE, T. H. M</creatorcontrib><title>CT and MR distinction of adenomas and nonadenomas of the adrenal gland</title><title>Journal of computer assisted tomography</title><addtitle>J Comput Assist Tomogr</addtitle><description>Because the distinction between adenomas and nonadenomas of the adrenal gland is essential, we investigated which of the following parameters--size, CT attenuation values, MRI signal intensity ratios on T1- and T2-weighted sequences, calculated T2 relaxation times, or T2 relaxation time ratios--provides better discrimination.
We compared these parameters in 44 adrenal masses of 37 patients by means of the Student t test and receiver operating characteristics (ROC) analyses.
Only size, CT attenuation values, and signal intensity ratios on T2-weighted MR images of adenomas showed a significant difference from those of nonadenomas. With use of ROC analysis, CT demonstrated a significantly larger area under the curve compared to size and T2 signal intensity ratios, indicating superior performance.
We found attenuation values on non-contrast-enhanced CT to be the best method in discriminating adrenal adenomas from nonadenomas. Adrenal masses with CT attenuation values below 15 HU warrant no further investigations.</description><subject>Adenoma - diagnosis</subject><subject>Adenoma - diagnostic imaging</subject><subject>Adrenal Gland Neoplasms - diagnosis</subject><subject>Adrenal Gland Neoplasms - diagnostic imaging</subject><subject>Adrenal Glands - diagnostic imaging</subject><subject>Adrenal Glands - pathology</subject><subject>Adrenals. Adrenal axis. Renin-angiotensin system (diseases)</subject><subject>Adrenocortical Adenoma - diagnosis</subject><subject>Adrenocortical Adenoma - diagnostic imaging</subject><subject>Adult</subject><subject>Aged</subject><subject>Biological and medical sciences</subject><subject>Diagnosis, Differential</subject><subject>Endocrinopathies</subject><subject>Female</subject><subject>Humans</subject><subject>Magnetic Resonance Imaging</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Non tumoral diseases. Target tissue resistance. Benign neoplasms</subject><subject>ROC Curve</subject><subject>Tomography, X-Ray Computed</subject><issn>0363-8715</issn><issn>1532-3145</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1994</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kF9LwzAUxYMoc04_gtAH8a2aNH-aPMpwKkwEmc_hNk200qYz6R789mZb7YVwuZxzbw4_hDKC7whW5T1OxcpC5kQphnma8vRIeYLmhNMip4TxUzTHVNBcloSfo4sYv_cOStkMzSSRUpFijlbLTQa-zl7fs7qJQ-PN0PQ-610GtfV9B_Eg-95Pc9KGL5v0YD202WebDJfozEEb7dXYF-hj9bhZPufrt6eX5cM6NynlkHNZKZDKARaGCCcttdzZgplaKMxZAULgSnKjgPOqqGQNhDLhHFcggAtLF-j2eHcb-p-djYPummhsmzLYfhd1KZiSXNFklEejCX2MwTq9DU0H4VcTrPcI9T9CPSHUB4Rp9Xr8Y1d1tp4WR2ZJvxl1iAZaF8CbJk42hkuZQtM_ibN3pw</recordid><startdate>19940501</startdate><enddate>19940501</enddate><creator>VAN ERKEL, A. R</creator><creator>VAN GILS, A. P. G</creator><creator>LEQUIN, M</creator><creator>KRUITWAGEN, C</creator><creator>BLOEM, J. L</creator><creator>FALKE, T. H. 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M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c405t-58b9a89fa06c16f8e3e5fe24cd690542a660b85c9a55b2b8da1346ff59a6a56e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1994</creationdate><topic>Adenoma - diagnosis</topic><topic>Adenoma - diagnostic imaging</topic><topic>Adrenal Gland Neoplasms - diagnosis</topic><topic>Adrenal Gland Neoplasms - diagnostic imaging</topic><topic>Adrenal Glands - diagnostic imaging</topic><topic>Adrenal Glands - pathology</topic><topic>Adrenals. Adrenal axis. Renin-angiotensin system (diseases)</topic><topic>Adrenocortical Adenoma - diagnosis</topic><topic>Adrenocortical Adenoma - diagnostic imaging</topic><topic>Adult</topic><topic>Aged</topic><topic>Biological and medical sciences</topic><topic>Diagnosis, Differential</topic><topic>Endocrinopathies</topic><topic>Female</topic><topic>Humans</topic><topic>Magnetic Resonance Imaging</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Non tumoral diseases. Target tissue resistance. Benign neoplasms</topic><topic>ROC Curve</topic><topic>Tomography, X-Ray Computed</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>VAN ERKEL, A. R</creatorcontrib><creatorcontrib>VAN GILS, A. P. G</creatorcontrib><creatorcontrib>LEQUIN, M</creatorcontrib><creatorcontrib>KRUITWAGEN, C</creatorcontrib><creatorcontrib>BLOEM, J. L</creatorcontrib><creatorcontrib>FALKE, T. H. 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M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>CT and MR distinction of adenomas and nonadenomas of the adrenal gland</atitle><jtitle>Journal of computer assisted tomography</jtitle><addtitle>J Comput Assist Tomogr</addtitle><date>1994-05-01</date><risdate>1994</risdate><volume>18</volume><issue>3</issue><spage>432</spage><epage>438</epage><pages>432-438</pages><issn>0363-8715</issn><eissn>1532-3145</eissn><coden>JCATD5</coden><abstract>Because the distinction between adenomas and nonadenomas of the adrenal gland is essential, we investigated which of the following parameters--size, CT attenuation values, MRI signal intensity ratios on T1- and T2-weighted sequences, calculated T2 relaxation times, or T2 relaxation time ratios--provides better discrimination.
We compared these parameters in 44 adrenal masses of 37 patients by means of the Student t test and receiver operating characteristics (ROC) analyses.
Only size, CT attenuation values, and signal intensity ratios on T2-weighted MR images of adenomas showed a significant difference from those of nonadenomas. With use of ROC analysis, CT demonstrated a significantly larger area under the curve compared to size and T2 signal intensity ratios, indicating superior performance.
We found attenuation values on non-contrast-enhanced CT to be the best method in discriminating adrenal adenomas from nonadenomas. Adrenal masses with CT attenuation values below 15 HU warrant no further investigations.</abstract><cop>Hagerstown, MD</cop><pub>Lippincott</pub><pmid>8188912</pmid><doi>10.1097/00004728-199405000-00017</doi><tpages>7</tpages></addata></record> |
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| ispartof | Journal of computer assisted tomography, 1994-05, Vol.18 (3), p.432-438 |
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| subjects | Adenoma - diagnosis Adenoma - diagnostic imaging Adrenal Gland Neoplasms - diagnosis Adrenal Gland Neoplasms - diagnostic imaging Adrenal Glands - diagnostic imaging Adrenal Glands - pathology Adrenals. Adrenal axis. Renin-angiotensin system (diseases) Adrenocortical Adenoma - diagnosis Adrenocortical Adenoma - diagnostic imaging Adult Aged Biological and medical sciences Diagnosis, Differential Endocrinopathies Female Humans Magnetic Resonance Imaging Male Medical sciences Middle Aged Non tumoral diseases. Target tissue resistance. Benign neoplasms ROC Curve Tomography, X-Ray Computed |
| title | CT and MR distinction of adenomas and nonadenomas of the adrenal gland |
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