Quantitative detection of hepatitis C virus RNA with a solid‐phase signal amplification method: Definition of optimal conditions for specimen collection and clinical application in interferon‐treated patients

To determine the optimal conditions for preparation of serum specimens for quantitative hepatitis C virus RNA determination, patient samples were processed such that differences in time from clot formation to centrifugation, centrifugation to separation of serum and collection of serum until freezin...

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Veröffentlicht in:	Hepatology (Baltimore, Md.) Md.), 1994-06, Vol.19 (6), p.1337-1341
Hauptverfasser:	Davis, Gary L., Lau, Johnson Y.‐N., Urdea, Mickie S., Neuwald, Paul D., Wilber, Judith C., Lindsay, Karen, Perrillo, Robert P., Albrecht, Janice
Format:	Artikel
Sprache:	eng
Schlagworte:	Alanine Transaminase - blood Base Sequence Centrifugation DNA Primers - chemistry DNA Probes - chemistry Hepacivirus - genetics Hepacivirus - isolation & purification Hepatitis C - microbiology Hepatitis C - therapy Humans Interferon-alpha - therapeutic use Molecular Sequence Data Polymerase Chain Reaction Recombinant Proteins Recurrence Retrospective Studies RNA, Viral - blood Sensitivity and Specificity Specimen Handling - methods Time Factors
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