Cystic fibrosis gene therapy using an adenovirus vector: in vivo safety and efficacy in nasal epithelium
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| Veröffentlicht in: | Human gene therapy 1994-02, Vol.5 (2), p.209-219 |
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| container_end_page | 219 |
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| container_issue | 2 |
| container_start_page | 209 |
| container_title | Human gene therapy |
| container_volume | 5 |
| creator | Welsh, M J Smith, A E Zabner, J Rich, D P Graham, S M Gregory, R J Pratt, B M Moscicki, R A |
| description | |
| doi_str_mv | 10.1089/hum.1994.5.2-209 |
| format | Article |
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Smith, A E ; Zabner, J ; Rich, D P ; Graham, S M ; Gregory, R J ; Pratt, B M ; Moscicki, R A</creator><creatorcontrib>Welsh, M J ; Smith, A E ; Zabner, J ; Rich, D P ; Graham, S M ; Gregory, R J ; Pratt, B M ; Moscicki, R A</creatorcontrib><identifier>ISSN: 1043-0342</identifier><identifier>DOI: 10.1089/hum.1994.5.2-209</identifier><identifier>PMID: 7514450</identifier><language>eng</language><publisher>United States</publisher><subject>adenovirus ; Adenoviruses, Human - physiology ; Administration, Intranasal ; Clinical Protocols ; Containment of Biohazards ; Cystic Fibrosis - genetics ; Cystic Fibrosis - therapy ; Cystic Fibrosis Transmembrane Conductance Regulator ; Defective Viruses - physiology ; Epithelium ; Evaluation Studies as Topic ; Genetic Therapy - adverse effects ; Genetic Therapy - methods ; Genetic Vectors ; Humans ; Membrane Proteins - genetics ; Nasal Mucosa ; Risk ; Safety ; Virus Replication</subject><ispartof>Human gene therapy, 1994-02, Vol.5 (2), p.209-219</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/7514450$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Welsh, M J</creatorcontrib><creatorcontrib>Smith, A E</creatorcontrib><creatorcontrib>Zabner, J</creatorcontrib><creatorcontrib>Rich, D P</creatorcontrib><creatorcontrib>Graham, S M</creatorcontrib><creatorcontrib>Gregory, R J</creatorcontrib><creatorcontrib>Pratt, B M</creatorcontrib><creatorcontrib>Moscicki, R A</creatorcontrib><title>Cystic fibrosis gene therapy using an adenovirus vector: in vivo safety and efficacy in nasal epithelium</title><title>Human gene therapy</title><addtitle>Hum Gene Ther</addtitle><subject>adenovirus</subject><subject>Adenoviruses, Human - physiology</subject><subject>Administration, Intranasal</subject><subject>Clinical Protocols</subject><subject>Containment of Biohazards</subject><subject>Cystic Fibrosis - genetics</subject><subject>Cystic Fibrosis - therapy</subject><subject>Cystic Fibrosis Transmembrane Conductance Regulator</subject><subject>Defective Viruses - physiology</subject><subject>Epithelium</subject><subject>Evaluation Studies as Topic</subject><subject>Genetic Therapy - adverse effects</subject><subject>Genetic Therapy - methods</subject><subject>Genetic Vectors</subject><subject>Humans</subject><subject>Membrane Proteins - genetics</subject><subject>Nasal Mucosa</subject><subject>Risk</subject><subject>Safety</subject><subject>Virus Replication</subject><issn>1043-0342</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1994</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkDlPwzAARj2ASinsLEie2BJ8H2yo4pIqscAc2Y7TGuXCjiPl31NEd6Zv-J7e8AC4wajESOn7Q-5KrDUreUkKgvQZWGPEaIEoIxfgMqUvhDDlQq7ASnLMGEdrcNguaQoONsHGIYUE9773cDr4aMYF5hT6PTQ9NLXvhznEnODs3TTEBxh6OId5gMk0flqOUA190wRn3PL79SaZFvoxHF1tyN0VOG9Mm_z1aTfg8_npY_ta7N5f3raPu2IkVE6FItozoZzjiDpnZSOs0DUnUlOiHJK2xkwSrAwTyBFNFZWkRsZZbBUijaYbcPfnHePwnX2aqi4k59vW9H7IqZKCKaU0-hfEQnPyG3ADbk9gtp2vqzGGzsSlOjWkP6zVckc</recordid><startdate>19940201</startdate><enddate>19940201</enddate><creator>Welsh, M J</creator><creator>Smith, A E</creator><creator>Zabner, J</creator><creator>Rich, D P</creator><creator>Graham, S M</creator><creator>Gregory, R J</creator><creator>Pratt, B M</creator><creator>Moscicki, R A</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7QO</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope><scope>7X8</scope></search><sort><creationdate>19940201</creationdate><title>Cystic fibrosis gene therapy using an adenovirus vector: in vivo safety and efficacy in nasal epithelium</title><author>Welsh, M J ; 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| fulltext | fulltext |
| identifier | ISSN: 1043-0342 |
| ispartof | Human gene therapy, 1994-02, Vol.5 (2), p.209-219 |
| issn | 1043-0342 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_76488890 |
| source | Mary Ann Liebert Online Subscription; MEDLINE |
| subjects | adenovirus Adenoviruses, Human - physiology Administration, Intranasal Clinical Protocols Containment of Biohazards Cystic Fibrosis - genetics Cystic Fibrosis - therapy Cystic Fibrosis Transmembrane Conductance Regulator Defective Viruses - physiology Epithelium Evaluation Studies as Topic Genetic Therapy - adverse effects Genetic Therapy - methods Genetic Vectors Humans Membrane Proteins - genetics Nasal Mucosa Risk Safety Virus Replication |
| title | Cystic fibrosis gene therapy using an adenovirus vector: in vivo safety and efficacy in nasal epithelium |
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