Clonal analysis of posttransplant lymphoproliferative disorders, using both episomal Epstein-Barr virus and immunoglobulin genes as markers

The authors analyzed the clonality of 15 samples of B-cell lymphoproliferations arising in eight organ allograft recipients, using immunoglobulin (Ig) gene rearrangement and the fused terminal fragment of episomal Epstein-Barr virus (EBV) DNA as independent clonal markers. The tumors arose from 1 mo...

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Veröffentlicht in:	American journal of clinical pathology 1994-05, Vol.101 (5), p.590-596
Hauptverfasser:	KAPLAN, M. A, FERRY, J. A, HARRIS, N. L, JACOBSON, J. O
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences Clone Cells DNA, Viral - analysis Female Gene Rearrangement, B-Lymphocyte - genetics Genes, Immunoglobulin - genetics Hematologic and hematopoietic diseases Herpesvirus 4, Human - genetics Humans Immunophenotyping Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Lymphoma, B-Cell - genetics Lymphoproliferative Disorders - genetics Lymphoproliferative Disorders - immunology Lymphoproliferative Disorders - microbiology Male Medical sciences Middle Aged Transplantation, Homologous - adverse effects
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