Specific Binding of Estrogen to Osteoclast Surfaces

Specific plasma membrane binding sites for 17β-estradiol were shown to exist on avian osteoclasts by the use of a fluorescent conjugated estrogen, 17β-estradiol -6- carboxymethyloxime- bovine serum albumin fluorescein isothiocyanate. Binding was dose and time dependent, as well as specific, since 17...

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Veröffentlicht in:	Biochemical and biophysical research communications 1994-04, Vol.200 (2), p.899-907
Hauptverfasser:	Brubaker, K.D., Gay, C.V.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acids - metabolism Animals Aves Binding Sites Binding, Competitive Biological and medical sciences Cell Membrane - metabolism Cell Size - drug effects Chickens Estradiol - analogs & derivatives Estradiol - metabolism Estradiol - pharmacology Estrogens, Conjugated (USP) - metabolism Estrogens, Conjugated (USP) - pharmacology Fluorescein-5-isothiocyanate - analogs & derivatives Fluorescein-5-isothiocyanate - metabolism Fluorescein-5-isothiocyanate - pharmacology Hormones. Endocrine system In Vitro Techniques Kinetics Medical sciences Osteoclasts - cytology Osteoclasts - drug effects Osteoclasts - metabolism Pharmacology. Drug treatments Receptors, Estradiol - metabolism Serum Albumin, Bovine - metabolism Serum Albumin, Bovine - pharmacology
Online-Zugang:	Volltext
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