Fractionated versus single-dose total body irradiation at low and high dose rates to condition canine littermates for DLA-identical marrow grafts

We explored in dogs the immunosuppressive properties of 450 cGy total body irradiation (TBI) delivered from two opposing 60Co sources, as assessed by the criterion of successful engraftment of allogeneic genotypically DLA-identical littermate marrow. Two questions were asked in this study. Firstly,...

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Veröffentlicht in:	Blood 1994-06, Vol.83 (11), p.3384-3389
Hauptverfasser:	STORB, R, RAFF, R. F, APPELBAUM, F. R, DEEG, H. J, GRAHAM, T. C, SCHUENING, F. G, SALE, G, BRYANT, E, SEIDEL, K
Format:	Artikel
Sprache:	eng
Schlagworte:	Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Animals Biological and medical sciences Bone Marrow Transplantation Bone marrow, stem cells transplantation. Graft versus host reaction Dogs Histocompatibility Antigens - immunology Histocompatibility Antigens Class I Medical sciences Radiation Dosage Transfusions. Complications. Transfusion reactions. Cell and gene therapy Whole-Body Irradiation
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