Glycosaminoglycan production in cultures of early and late passage human endothelial cells: The influence of an anionic endothelial cell growth factor and the extracellular matrix

An endothelial cell (EC) growth factor isolated from bovine brain stimulates in vitro growth of human umbilical vein endothelial cells, and permits long term serial propagation. In the presence of increasing concentrations of EC growth factor, confluent cultures of early (CPDL ⩽ 20) and late (CPDL &...

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Veröffentlicht in:	Journal of cellular physiology 1985-12, Vol.125 (3), p.596-607
Hauptverfasser:	Gordon, Portia B., Conn, Greg, Hatcher, Victor B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Cell Adhesion - drug effects Cell Membrane - enzymology Cell metabolism, cell oxidation Cell physiology Cells, Cultured Endothelial Growth Factors Endothelium - cytology Endothelium - enzymology Endothelium - metabolism Extracellular Matrix - metabolism Extracellular Matrix - physiology Fundamental and applied biological sciences. Psychology Glucosamine - metabolism Glycosaminoglycans - biosynthesis Glycosaminoglycans - metabolism Growth Substances - physiology Heparitin Sulfate - metabolism Humans Leucine - metabolism Molecular and cellular biology Proteins - metabolism Time Factors Umbilical Veins
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