Flow cytometric study of idarubicin and daunorubicin accumulation and the effect of verapamil in leukemic cell lines and fresh cells from patients with acute non-lymphoblastic leukemia

By using flow cytometry, the intracellular accumulation (Acc) of idarubicin (IDA) and daunorubicin (DNR) and the effect of verapamil (VRP) on both anthracycline accumulation (VRP) index) were studied in leukemic cell lines (K562 and HL60 and their two DNR-resistant subclones) and fresh leukemic cell...

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Veröffentlicht in:Leukemia research 1994-05, Vol.18 (5), p.313-318
Hauptverfasser: Boiron, Jean-Michel, Belloc, Francis, Montastruc, Marion, Cony-Makhoul, Pascale, Dumain, Patrice, Marit, Gérald, Mahon, François-Xavier, Puntous, Maryse, Lopez, Francis, Lacombe, Francis, Reiffers, Josy
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Sprache:eng
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