Identification and characterization of a lysophosphatidic acid receptor

A specific binding site for 1-[3H]stearoyl-lysophosphatidic acid (stearoyl-LPA) was identified and characterized in membranes prepared from rat brain and Swiss 3T3 fibroblasts. Specific binding of [3H]LPA to these sites was protein dependent, was saturable, reached equilibrium in 15 min, and was dis...

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Veröffentlicht in:	Molecular pharmacology 1994-04, Vol.45 (4), p.718-723
Hauptverfasser:	Thomson, F J, Perkins, L, Ahern, D, Clark, M
Format:	Artikel
Sprache:	eng
Schlagworte:	3T3 Cells Animals Biological and medical sciences Brain - metabolism Calcium - metabolism Cell Membrane - metabolism Cell receptors Cell structures and functions Fundamental and applied biological sciences. Psychology In Vitro Techniques Male Mice Miscellaneous Molecular and cellular biology Radioligand Assay Rats Rats, Sprague-Dawley Receptors, Cell Surface - chemistry Receptors, Cell Surface - metabolism Receptors, G-Protein-Coupled Receptors, Lysophosphatidic Acid Tissue Distribution
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