Genetic control of early neuronal development in vertebrates
The specification of neuronal fate starts with cell commitment and determination. These early events are accompanied by rearrangement and reshaping of presumptive neural cells. Later, the neural differentiation begins, and its course can be followed using specific molecular markers. Such events take...
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Veröffentlicht in: | Current opinion in neurobiology 1994, Vol.4 (1), p.21-28 |
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description | The specification of neuronal fate starts with cell commitment and determination. These early events are accompanied by rearrangement and reshaping of presumptive neural cells. Later, the neural differentiation begins, and its course can be followed using specific molecular markers. Such events take place long before the cells acquire a typical neuronal phenotype. Primary neurons of lower vertebrates differ from secondary neurons by their size, position, timing of differentiation and length of axon. Primary neurons start to express early markers of neural differentiation at the end of gastrulation. Recent data indicate that in lower vertebrates the neural induction of primary neurons differs from the induction of secondary neurons; however, neural induction in higher vertebrates appears to be similar to the induction of secondary neurons in lower vertebrates. |
doi_str_mv | 10.1016/0959-4388(94)90027-2 |
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Recent data indicate that in lower vertebrates the neural induction of primary neurons differs from the induction of secondary neurons; however, neural induction in higher vertebrates appears to be similar to the induction of secondary neurons in lower vertebrates.</description><subject>Animals</subject><subject>Cell Differentiation</subject><subject>Mutation</subject><subject>Nervous System - embryology</subject><subject>Neurons - cytology</subject><subject>Neurons - physiology</subject><subject>Signal Transduction</subject><subject>Vertebrata</subject><subject>Vertebrates - embryology</subject><subject>Vertebrates - genetics</subject><issn>0959-4388</issn><issn>1873-6882</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1994</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkM9LwzAYhoMoc07_A4WeRA_V_GibBESQoVMYeNFzSJMvEGmbmbSD_fd2buyop-_wPu_7wYPQJcF3BJPqHstS5gUT4kYWtxJjynN6hKZEcJZXQtBjND0gp-gspS-MccUEm6CJIJwxSqboYQEd9N5kJnR9DE0WXAY6NpusgyGGTjeZhTU0YdVC12e-y9YQe6ij7iGdoxOnmwQX-ztDny_PH_PXfPm-eJs_LXPDKtnnvOLOYuq0kbS20mGwDLDkhDsK2JaOSUJr7grCteYYpAVRixpqZjAtjWEzdL3bXcXwPUDqVeuTgabRHYQhKV4VnAsi_gVJxYUQZTmCxQ40MaQUwalV9K2OG0Ww2tpVW3Vqq07JQv3aVXSsXe33h7oFeyjtdY754y6H0cbaQ1TJeOgMWB_B9MoG__eDH8BIibk</recordid><startdate>1994</startdate><enddate>1994</enddate><creator>Korzh, Vladimir P.</creator><general>Elsevier Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TK</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope><scope>RC3</scope><scope>7X8</scope></search><sort><creationdate>1994</creationdate><title>Genetic control of early neuronal development in vertebrates</title><author>Korzh, Vladimir P.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c369t-767fd02fac92bd9f0ed3e09717f2e0d5f3912b7f417aa70e9de8b8beb3c025cc3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1994</creationdate><topic>Animals</topic><topic>Cell Differentiation</topic><topic>Mutation</topic><topic>Nervous System - embryology</topic><topic>Neurons - cytology</topic><topic>Neurons - physiology</topic><topic>Signal Transduction</topic><topic>Vertebrata</topic><topic>Vertebrates - embryology</topic><topic>Vertebrates - genetics</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Korzh, Vladimir P.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Neurosciences Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Current opinion in neurobiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Korzh, Vladimir P.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Genetic control of early neuronal development in vertebrates</atitle><jtitle>Current opinion in neurobiology</jtitle><addtitle>Curr Opin Neurobiol</addtitle><date>1994</date><risdate>1994</risdate><volume>4</volume><issue>1</issue><spage>21</spage><epage>28</epage><pages>21-28</pages><issn>0959-4388</issn><eissn>1873-6882</eissn><abstract>The specification of neuronal fate starts with cell commitment and determination. 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subjects | Animals Cell Differentiation Mutation Nervous System - embryology Neurons - cytology Neurons - physiology Signal Transduction Vertebrata Vertebrates - embryology Vertebrates - genetics |
title | Genetic control of early neuronal development in vertebrates |
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