Dobutamine: A hemodynamic evaluation in pulmonary embolism shock
Intravenous dobutamine was used in ten patients requiring aggressive therapy for massive pulmonary embolism with circulatory failure. Except in one patient who rapidly died, a 30-min dobutamine infusion (8.3 ± 2.7 μg/kg±min) increased both cardiac index (from 1.7 ± 0.4 to 2.3 ± 0.6 L/min ± m, p <...
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| Veröffentlicht in: | Critical care medicine 1985-12, Vol.13 (12), p.1009-1012 |
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| container_title | Critical care medicine |
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| creator | JARDIN, FRANÇOIS GENEVRAY, BRUNO BRUN-NEY, DOMINIQUE MARGAIRAZ, ANDRE |
| description | Intravenous dobutamine was used in ten patients requiring aggressive therapy for massive pulmonary embolism with circulatory failure. Except in one patient who rapidly died, a 30-min dobutamine infusion (8.3 ± 2.7 μg/kg±min) increased both cardiac index (from 1.7 ± 0.4 to 2.3 ± 0.6 L/min ± m, p < .001) and stroke index (from 16.6 ± 6.7 to 21 ± 5 ml/m, p < .01), and also reduced pulmonary vascular resistance. Additional hemodynamic improvement was observed until weaning from dobutamine, which was successfully completed 3.3 ± 0.9 days after the start of infusion. |
| doi_str_mv | 10.1097/00003246-198512000-00004 |
| format | Article |
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Except in one patient who rapidly died, a 30-min dobutamine infusion (8.3 ± 2.7 μg/kg±min) increased both cardiac index (from 1.7 ± 0.4 to 2.3 ± 0.6 L/min ± m, p < .001) and stroke index (from 16.6 ± 6.7 to 21 ± 5 ml/m, p < .01), and also reduced pulmonary vascular resistance. Additional hemodynamic improvement was observed until weaning from dobutamine, which was successfully completed 3.3 ± 0.9 days after the start of infusion.</description><identifier>ISSN: 0090-3493</identifier><identifier>EISSN: 1530-0293</identifier><identifier>DOI: 10.1097/00003246-198512000-00004</identifier><identifier>PMID: 4064710</identifier><identifier>CODEN: CCMDC7</identifier><language>eng</language><publisher>Hagerstown, MD: Williams & Wilkins</publisher><subject>Adult ; Aged ; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy ; Biological and medical sciences ; Blood Pressure - drug effects ; Cardiac Output - drug effects ; Dobutamine - administration & dosage ; Dobutamine - pharmacology ; Dobutamine - therapeutic use ; Emergency and intensive cardiocirculatory care. Cardiogenic shock. Coronary intensive care ; Female ; Heart Rate - drug effects ; Hemodynamics - drug effects ; Humans ; Infusions, Parenteral ; Intensive care medicine ; Male ; Medical sciences ; Middle Aged ; Oxygen - blood ; Oxygen Consumption ; Pulmonary Embolism - complications ; Pulmonary Embolism - drug therapy ; Pulmonary Embolism - physiopathology ; Pulmonary Wedge Pressure - drug effects ; Shock - drug therapy ; Shock - etiology ; Shock - physiopathology ; Vascular Resistance - drug effects</subject><ispartof>Critical care medicine, 1985-12, Vol.13 (12), p.1009-1012</ispartof><rights>Williams & Wilkins 1985. All Rights Reserved.</rights><rights>1986 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4504-2e75f368df60d0ae413a4cc03f52bb01496f18f61204bff978a46f871215e0883</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=8509081$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/4064710$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>JARDIN, FRANÇOIS</creatorcontrib><creatorcontrib>GENEVRAY, BRUNO</creatorcontrib><creatorcontrib>BRUN-NEY, DOMINIQUE</creatorcontrib><creatorcontrib>MARGAIRAZ, ANDRE</creatorcontrib><title>Dobutamine: A hemodynamic evaluation in pulmonary embolism shock</title><title>Critical care medicine</title><addtitle>Crit Care Med</addtitle><description>Intravenous dobutamine was used in ten patients requiring aggressive therapy for massive pulmonary embolism with circulatory failure. Except in one patient who rapidly died, a 30-min dobutamine infusion (8.3 ± 2.7 μg/kg±min) increased both cardiac index (from 1.7 ± 0.4 to 2.3 ± 0.6 L/min ± m, p < .001) and stroke index (from 16.6 ± 6.7 to 21 ± 5 ml/m, p < .01), and also reduced pulmonary vascular resistance. Additional hemodynamic improvement was observed until weaning from dobutamine, which was successfully completed 3.3 ± 0.9 days after the start of infusion.</description><subject>Adult</subject><subject>Aged</subject><subject>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</subject><subject>Biological and medical sciences</subject><subject>Blood Pressure - drug effects</subject><subject>Cardiac Output - drug effects</subject><subject>Dobutamine - administration & dosage</subject><subject>Dobutamine - pharmacology</subject><subject>Dobutamine - therapeutic use</subject><subject>Emergency and intensive cardiocirculatory care. Cardiogenic shock. Coronary intensive care</subject><subject>Female</subject><subject>Heart Rate - drug effects</subject><subject>Hemodynamics - drug effects</subject><subject>Humans</subject><subject>Infusions, Parenteral</subject><subject>Intensive care medicine</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Oxygen - blood</subject><subject>Oxygen Consumption</subject><subject>Pulmonary Embolism - complications</subject><subject>Pulmonary Embolism - drug therapy</subject><subject>Pulmonary Embolism - physiopathology</subject><subject>Pulmonary Wedge Pressure - drug effects</subject><subject>Shock - drug therapy</subject><subject>Shock - etiology</subject><subject>Shock - physiopathology</subject><subject>Vascular Resistance - drug effects</subject><issn>0090-3493</issn><issn>1530-0293</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1985</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kU1PwzAMhiMEGmPwE5ByQNwKTpO2KSem8SlN4gLnKE0TtSxtRtMy7d-TsbIbuUSv_dix3yCECdwQyLNbCIfGLI1IzhMSBxXtQuwITUlCg4hzeoymADlElOX0FJ15_wlAWJLRCZowSFlGYIruH1wx9LKpW32H57jSjSu3bdAK629pB9nXrsV1i9eDbVwruy3WTeFs7RvsK6dW5-jESOv1xXjP0MfT4_viJVq-Pb8u5stIsQRYFOssMTTlpUmhBKkZoZIpBdQkcVGEufLUEG7SsAsrjMkzLllqeEZikmjgnM7Q9b7vunNfg_a9aGqvtLWy1W7wItstlBMIIN-DqnPed9qIdVc3YXBBQOzME3_miYN5vyEWSi_HN4ai0eWhcHQr5K_GvPRKWtPJVtX-gPEk2M1JwNge2zjb686v7LDRnai0tH0l_vs6-gPFY4Tg</recordid><startdate>198512</startdate><enddate>198512</enddate><creator>JARDIN, FRANÇOIS</creator><creator>GENEVRAY, BRUNO</creator><creator>BRUN-NEY, DOMINIQUE</creator><creator>MARGAIRAZ, ANDRE</creator><general>Williams & Wilkins</general><general>Lippincott</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>198512</creationdate><title>Dobutamine: A hemodynamic evaluation in pulmonary embolism shock</title><author>JARDIN, FRANÇOIS ; GENEVRAY, BRUNO ; BRUN-NEY, DOMINIQUE ; MARGAIRAZ, ANDRE</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4504-2e75f368df60d0ae413a4cc03f52bb01496f18f61204bff978a46f871215e0883</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1985</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</topic><topic>Biological and medical sciences</topic><topic>Blood Pressure - drug effects</topic><topic>Cardiac Output - drug effects</topic><topic>Dobutamine - administration & dosage</topic><topic>Dobutamine - pharmacology</topic><topic>Dobutamine - therapeutic use</topic><topic>Emergency and intensive cardiocirculatory care. Cardiogenic shock. Coronary intensive care</topic><topic>Female</topic><topic>Heart Rate - drug effects</topic><topic>Hemodynamics - drug effects</topic><topic>Humans</topic><topic>Infusions, Parenteral</topic><topic>Intensive care medicine</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Oxygen - blood</topic><topic>Oxygen Consumption</topic><topic>Pulmonary Embolism - complications</topic><topic>Pulmonary Embolism - drug therapy</topic><topic>Pulmonary Embolism - physiopathology</topic><topic>Pulmonary Wedge Pressure - drug effects</topic><topic>Shock - drug therapy</topic><topic>Shock - etiology</topic><topic>Shock - physiopathology</topic><topic>Vascular Resistance - drug effects</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>JARDIN, FRANÇOIS</creatorcontrib><creatorcontrib>GENEVRAY, BRUNO</creatorcontrib><creatorcontrib>BRUN-NEY, DOMINIQUE</creatorcontrib><creatorcontrib>MARGAIRAZ, ANDRE</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Critical care medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>JARDIN, FRANÇOIS</au><au>GENEVRAY, BRUNO</au><au>BRUN-NEY, DOMINIQUE</au><au>MARGAIRAZ, ANDRE</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Dobutamine: A hemodynamic evaluation in pulmonary embolism shock</atitle><jtitle>Critical care medicine</jtitle><addtitle>Crit Care Med</addtitle><date>1985-12</date><risdate>1985</risdate><volume>13</volume><issue>12</issue><spage>1009</spage><epage>1012</epage><pages>1009-1012</pages><issn>0090-3493</issn><eissn>1530-0293</eissn><coden>CCMDC7</coden><abstract>Intravenous dobutamine was used in ten patients requiring aggressive therapy for massive pulmonary embolism with circulatory failure. Except in one patient who rapidly died, a 30-min dobutamine infusion (8.3 ± 2.7 μg/kg±min) increased both cardiac index (from 1.7 ± 0.4 to 2.3 ± 0.6 L/min ± m, p < .001) and stroke index (from 16.6 ± 6.7 to 21 ± 5 ml/m, p < .01), and also reduced pulmonary vascular resistance. Additional hemodynamic improvement was observed until weaning from dobutamine, which was successfully completed 3.3 ± 0.9 days after the start of infusion.</abstract><cop>Hagerstown, MD</cop><pub>Williams & Wilkins</pub><pmid>4064710</pmid><doi>10.1097/00003246-198512000-00004</doi><tpages>4</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0090-3493 |
| ispartof | Critical care medicine, 1985-12, Vol.13 (12), p.1009-1012 |
| issn | 0090-3493 1530-0293 |
| language | eng |
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| source | MEDLINE; Journals@Ovid Complete |
| subjects | Adult Aged Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Biological and medical sciences Blood Pressure - drug effects Cardiac Output - drug effects Dobutamine - administration & dosage Dobutamine - pharmacology Dobutamine - therapeutic use Emergency and intensive cardiocirculatory care. Cardiogenic shock. Coronary intensive care Female Heart Rate - drug effects Hemodynamics - drug effects Humans Infusions, Parenteral Intensive care medicine Male Medical sciences Middle Aged Oxygen - blood Oxygen Consumption Pulmonary Embolism - complications Pulmonary Embolism - drug therapy Pulmonary Embolism - physiopathology Pulmonary Wedge Pressure - drug effects Shock - drug therapy Shock - etiology Shock - physiopathology Vascular Resistance - drug effects |
| title | Dobutamine: A hemodynamic evaluation in pulmonary embolism shock |
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