Reversal of pulmonary vascular remodelling following hypoxic exposure: no effect of infusion of atrial natriuretic factor and neutral endopeptidase inhibitor

Objective: The aim was to investigate whether infusion of either atrial natriuretic factor (ANF, 800 ng·h−1·rat−1) or a specific inhibitor of neutral endopeptidase 24.11 (NEI, UK 73,967, 5.4 mg·kg−1·d−1) can influence the reversal of the pulmonary vascular remodelling produced by exposure to hypoxia...

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