The UV response involving the ras signaling pathway and AP-1 transcription factors is conserved between yeast and mammals
UV irradiation of mammalian cells activates AP-1 through a Ras-dependent pathway, independently of DNA damage. We show that the yeast S. cerevisiae has a remarkably similar UV response involving the AP-1 factor Gcn4, which is distinct from the DNA damage response. Transcriptional activation of HIS3...
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Veröffentlicht in: | Cell 1994-05, Vol.77 (3), p.381-390 |
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