Prevention of coronary thrombosis with subthrombolytic doses of tissue-type plasminogen activator

To determine whether tissue-type plasminogen activator (t-PA) may prevent coronary thrombosis or accelerate the lysis of clot formed under conditions in which increased concentration of the activator is present before thrombosis, clot lysis studies were undertaken in vitro and in vivo. In vitro, exo...

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Veröffentlicht in:	Circulation (New York, N.Y.) N.Y.), 1985-12, Vol.72 (6), p.1346-1354
Hauptverfasser:	FOX, K. A. A, ROBISON, A. K, KNABB, R. M, ROSAMOND, T. L, SOBEL, B. E, BERGMANN, S. R
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Blood. Blood coagulation. Reticuloendothelial system Coronary Disease - prevention & control Dogs Fibrinolysis - drug effects Humans In Vitro Techniques Male Mathematics Medical sciences Models, Biological Pharmacology. Drug treatments Tissue Plasminogen Activator - administration & dosage Tissue Plasminogen Activator - pharmacology
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