Reversible jaundice in primary biliary cirrhosis due to hyperthyroidism
A patient with primary biliary cirrhosis had a dramatic deterioration in liver function with jaundice over 2 months as a result of development of Graves' disease. Clinical examination and radiological and cardiovascular investigations excluded heart failure and biliary obstruction as the cause...
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Veröffentlicht in: | Gastroenterology (New York, N.Y. 1943) N.Y. 1943), 1994-05, Vol.106 (5), p.1342-1343 |
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container_title | Gastroenterology (New York, N.Y. 1943) |
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creator | Thompson, Nick P. Leader, Serena Jamieson, Crawford P. Burnham, W.Rodney Burroughs, Andrew K. |
description | A patient with primary biliary cirrhosis had a dramatic deterioration in liver function with jaundice over 2 months as a result of development of Graves' disease. Clinical examination and radiological and cardiovascular investigations excluded heart failure and biliary obstruction as the cause of this deterioration. The patient's jaundice entirely reversed with treatment of hyperthyroidism, with bilirubin levels decreasing from 244 to 16 μmol/L (14.35 to 0.94 mg/dL). Deterioration in liver function in a patient with primary biliary cirrhosis as a result of hyperthyroidism has not previously been described. |
doi_str_mv | 10.1016/0016-5085(94)90028-0 |
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Clinical examination and radiological and cardiovascular investigations excluded heart failure and biliary obstruction as the cause of this deterioration. The patient's jaundice entirely reversed with treatment of hyperthyroidism, with bilirubin levels decreasing from 244 to 16 μmol/L (14.35 to 0.94 mg/dL). Deterioration in liver function in a patient with primary biliary cirrhosis as a result of hyperthyroidism has not previously been described.</description><identifier>ISSN: 0016-5085</identifier><identifier>EISSN: 1528-0012</identifier><identifier>DOI: 10.1016/0016-5085(94)90028-0</identifier><identifier>PMID: 8174893</identifier><identifier>CODEN: GASTAB</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Bilirubin - blood ; Biological and medical sciences ; Female ; Gastroenterology. Liver. Pancreas. Abdomen ; Humans ; Hyperthyroidism - complications ; Hyperthyroidism - physiopathology ; Jaundice - blood ; Jaundice - etiology ; Liver - pathology ; Liver - physiopathology ; Liver Cirrhosis, Biliary - complications ; Liver Cirrhosis, Biliary - pathology ; Liver Cirrhosis, Biliary - physiopathology ; Medical sciences ; Middle Aged ; Other diseases. Semiology ; Stomach. Duodenum. Small intestine. Colon. Rectum. 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Clinical examination and radiological and cardiovascular investigations excluded heart failure and biliary obstruction as the cause of this deterioration. The patient's jaundice entirely reversed with treatment of hyperthyroidism, with bilirubin levels decreasing from 244 to 16 μmol/L (14.35 to 0.94 mg/dL). Deterioration in liver function in a patient with primary biliary cirrhosis as a result of hyperthyroidism has not previously been described.</description><subject>Bilirubin - blood</subject><subject>Biological and medical sciences</subject><subject>Female</subject><subject>Gastroenterology. Liver. Pancreas. Abdomen</subject><subject>Humans</subject><subject>Hyperthyroidism - complications</subject><subject>Hyperthyroidism - physiopathology</subject><subject>Jaundice - blood</subject><subject>Jaundice - etiology</subject><subject>Liver - pathology</subject><subject>Liver - physiopathology</subject><subject>Liver Cirrhosis, Biliary - complications</subject><subject>Liver Cirrhosis, Biliary - pathology</subject><subject>Liver Cirrhosis, Biliary - physiopathology</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Other diseases. Semiology</subject><subject>Stomach. Duodenum. Small intestine. Colon. Rectum. 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Liver. Pancreas. Abdomen</topic><topic>Humans</topic><topic>Hyperthyroidism - complications</topic><topic>Hyperthyroidism - physiopathology</topic><topic>Jaundice - blood</topic><topic>Jaundice - etiology</topic><topic>Liver - pathology</topic><topic>Liver - physiopathology</topic><topic>Liver Cirrhosis, Biliary - complications</topic><topic>Liver Cirrhosis, Biliary - pathology</topic><topic>Liver Cirrhosis, Biliary - physiopathology</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Other diseases. Semiology</topic><topic>Stomach. Duodenum. Small intestine. Colon. Rectum. Anus</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Thompson, Nick P.</creatorcontrib><creatorcontrib>Leader, Serena</creatorcontrib><creatorcontrib>Jamieson, Crawford P.</creatorcontrib><creatorcontrib>Burnham, W.Rodney</creatorcontrib><creatorcontrib>Burroughs, Andrew K.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Gastroenterology (New York, N.Y. 1943)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Thompson, Nick P.</au><au>Leader, Serena</au><au>Jamieson, Crawford P.</au><au>Burnham, W.Rodney</au><au>Burroughs, Andrew K.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Reversible jaundice in primary biliary cirrhosis due to hyperthyroidism</atitle><jtitle>Gastroenterology (New York, N.Y. 1943)</jtitle><addtitle>Gastroenterology</addtitle><date>1994-05-01</date><risdate>1994</risdate><volume>106</volume><issue>5</issue><spage>1342</spage><epage>1343</epage><pages>1342-1343</pages><issn>0016-5085</issn><eissn>1528-0012</eissn><coden>GASTAB</coden><abstract>A patient with primary biliary cirrhosis had a dramatic deterioration in liver function with jaundice over 2 months as a result of development of Graves' disease. Clinical examination and radiological and cardiovascular investigations excluded heart failure and biliary obstruction as the cause of this deterioration. The patient's jaundice entirely reversed with treatment of hyperthyroidism, with bilirubin levels decreasing from 244 to 16 μmol/L (14.35 to 0.94 mg/dL). Deterioration in liver function in a patient with primary biliary cirrhosis as a result of hyperthyroidism has not previously been described.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>8174893</pmid><doi>10.1016/0016-5085(94)90028-0</doi><tpages>2</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Bilirubin - blood Biological and medical sciences Female Gastroenterology. Liver. Pancreas. Abdomen Humans Hyperthyroidism - complications Hyperthyroidism - physiopathology Jaundice - blood Jaundice - etiology Liver - pathology Liver - physiopathology Liver Cirrhosis, Biliary - complications Liver Cirrhosis, Biliary - pathology Liver Cirrhosis, Biliary - physiopathology Medical sciences Middle Aged Other diseases. Semiology Stomach. Duodenum. Small intestine. Colon. Rectum. Anus |
title | Reversible jaundice in primary biliary cirrhosis due to hyperthyroidism |
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