Enalapril maleate affects 2-oxoglutarate metabolism in mitochondria from the rat kidney cortex

Enalapril maleate (EM) is the salt of N‐{(S)‐1‐(ethoxycarbonyl)‐3‐phenylpropyl}‐L‐alanyl‐L‐proline, used therapeutically as an anti‐hypertensive agent. The effects of EM on some aspects of the energy metabolism and membrane properties of mitochondria from rat liver and kidney cortex were studied, bu...

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Veröffentlicht in:	Cell biochemistry and function 1994-01, Vol.12 (1), p.21-28
Hauptverfasser:	Merlin, Ma. Eliane, Campello, Annibal P., Klüppel, Ma. Lúcia W.
Format:	Artikel
Sprache:	eng
Schlagworte:	2-oxoglutarate dehydrogenase complex Animals anti-hypertensive Enalapril - pharmacology Enalapril maleate Ketoglutaric Acids - metabolism Kidney Cortex - drug effects Kidney Cortex - metabolism Kidney Cortex - ultrastructure liver and kidney cortex mitochondria Mitochondria - drug effects Mitochondria - metabolism Mitochondria, Liver - drug effects Mitochondria, Liver - metabolism oxidative phosphorylation oxygen uptake Prodrugs - pharmacology Rats transmembrane potential
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