C−H Bond Functionalization in the Synthesis of Fused 1,2,3-Triazoles
A highly modular approach to fused 1,2,3-triazoles has been developed featuring a one-pot procedure combining copper(I) catalyzed azide−alkyne cycloaddition and palladium-catalyzed C−H bond functionalization. A class of structurally unique heterocycles was synthesized in good yields.
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| Veröffentlicht in: | Organic letters 2010-11, Vol.12 (22), p.5092-5095 |
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| container_end_page | 5095 |
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| container_issue | 22 |
| container_start_page | 5092 |
| container_title | Organic letters |
| container_volume | 12 |
| creator | Panteleev, Jane Geyer, Karolin Aguilar-Aguilar, Angelica Wang, Letian Lautens, Mark |
| description | A highly modular approach to fused 1,2,3-triazoles has been developed featuring a one-pot procedure combining copper(I) catalyzed azide−alkyne cycloaddition and palladium-catalyzed C−H bond functionalization. A class of structurally unique heterocycles was synthesized in good yields. |
| doi_str_mv | 10.1021/ol102342y |
| format | Article |
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| fulltext | fulltext |
| identifier | ISSN: 1523-7060 |
| ispartof | Organic letters, 2010-11, Vol.12 (22), p.5092-5095 |
| issn | 1523-7060 1523-7052 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_764544601 |
| source | MEDLINE; ACS Publications |
| subjects | Alkynes - chemistry Azides - chemistry Catalysis Combinatorial Chemistry Techniques Copper - chemistry Cyclization Heterocyclic Compounds, 4 or More Rings - chemical synthesis Heterocyclic Compounds, 4 or More Rings - chemistry Molecular Structure Palladium - chemistry Triazoles - chemical synthesis Triazoles - chemistry |
| title | C−H Bond Functionalization in the Synthesis of Fused 1,2,3-Triazoles |
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