An Unusual Case of Primary Small Cell Neuroendocrine Carcinoma of the Breast
: Primary small cell neuroendocrine carcinoma of breast is a rare entity, with only case reports in literature. Histologically, these tumors are similar to small cell carcinoma of the lung with some evidence of ductal carcinoma‐in‐situ with areas of ductal, lobular, or papillary differentiation. Im...
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| Veröffentlicht in: | The breast journal 2010-11, Vol.16 (6), p.647-651 |
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| container_title | The breast journal |
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| creator | Latif, Naeem Rosa, Marilin Samian, Laila Rana, Fauzia |
| description | : Primary small cell neuroendocrine carcinoma of breast is a rare entity, with only case reports in literature. Histologically, these tumors are similar to small cell carcinoma of the lung with some evidence of ductal carcinoma‐in‐situ with areas of ductal, lobular, or papillary differentiation. Immunoreactivity for neuroendocrine markers is present in two thirds of cases, while 33–50% are positive for estrogen receptor or progesterone receptor. Her2/neu expression has not been reported in small cell carcinoma of the breast. Here we are presenting 53‐year‐old women with locally advanced primary small cell neuroendocrine carcinoma of breast. We will discuss clinicopathological findings, treatment options, prognosis and review of the literature on primary small cell carcinoma of breast. |
| doi_str_mv | 10.1111/j.1524-4741.2010.00974.x |
| format | Article |
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Histologically, these tumors are similar to small cell carcinoma of the lung with some evidence of ductal carcinoma‐in‐situ with areas of ductal, lobular, or papillary differentiation. Immunoreactivity for neuroendocrine markers is present in two thirds of cases, while 33–50% are positive for estrogen receptor or progesterone receptor. Her2/neu expression has not been reported in small cell carcinoma of the breast. Here we are presenting 53‐year‐old women with locally advanced primary small cell neuroendocrine carcinoma of breast. We will discuss clinicopathological findings, treatment options, prognosis and review of the literature on primary small cell carcinoma of breast.</description><subject>Breast Neoplasms - pathology</subject><subject>Carcinoma, Neuroendocrine - pathology</subject><subject>Carcinoma, Small Cell - pathology</subject><subject>Female</subject><subject>Humans</subject><subject>immunohistochemical</subject><subject>Middle Aged</subject><subject>neuroendocrine</subject><subject>Positron-Emission Tomography</subject><subject>Prognosis</subject><subject>small cell</subject><subject>Tomography, X-Ray Computed</subject><issn>1075-122X</issn><issn>1524-4741</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkE1PwzAMQCMEYjD4C6g3Ti1O6rapxGWb-NQESGwStyhLPdFpbUeyiu3fk7KxMzkklv3sJI-xgEPE_bpZRDwRGGKGPBLgswB5htHmiJ0dCsc-hiwJuRAfPXbu3AIARA54ynrCVwBRnLHxoA6mdetavQxG2lHQzIM3W1baboP3Si99lvz2Qq1tqC4aY8uaPGlNWTeV7vD1JwVDS9qtL9jJXC8dXe7PPpve301Gj-H49eFpNBiHBmWMoYZCiljOUsyBZGEMcp6hiRPBNQqT5KlGKSXwmdRCI2JhBBKR5BpymYu4z653c1e2-WrJrVVVOuPfqWtqWqeyFBOENEs9KXeksY1zluZqtfuc4qA6lWqhOmOqM6Y6lepXpdr41qv9Je2souLQ-OfOA7c74Ltc0vbfg9Vk-OyD-Ae4IH_X</recordid><startdate>201011</startdate><enddate>201011</enddate><creator>Latif, Naeem</creator><creator>Rosa, Marilin</creator><creator>Samian, Laila</creator><creator>Rana, Fauzia</creator><general>Blackwell Publishing Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>201011</creationdate><title>An Unusual Case of Primary Small Cell Neuroendocrine Carcinoma of the Breast</title><author>Latif, Naeem ; Rosa, Marilin ; Samian, Laila ; Rana, Fauzia</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4834-a0d8238b6490e8dcc41174c3521a42c596a488801b8a2a444dc24eee81a098923</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Breast Neoplasms - pathology</topic><topic>Carcinoma, Neuroendocrine - pathology</topic><topic>Carcinoma, Small Cell - pathology</topic><topic>Female</topic><topic>Humans</topic><topic>immunohistochemical</topic><topic>Middle Aged</topic><topic>neuroendocrine</topic><topic>Positron-Emission Tomography</topic><topic>Prognosis</topic><topic>small cell</topic><topic>Tomography, X-Ray Computed</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Latif, Naeem</creatorcontrib><creatorcontrib>Rosa, Marilin</creatorcontrib><creatorcontrib>Samian, Laila</creatorcontrib><creatorcontrib>Rana, Fauzia</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The breast journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Latif, Naeem</au><au>Rosa, Marilin</au><au>Samian, Laila</au><au>Rana, Fauzia</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>An Unusual Case of Primary Small Cell Neuroendocrine Carcinoma of the Breast</atitle><jtitle>The breast journal</jtitle><addtitle>Breast J</addtitle><date>2010-11</date><risdate>2010</risdate><volume>16</volume><issue>6</issue><spage>647</spage><epage>651</epage><pages>647-651</pages><issn>1075-122X</issn><eissn>1524-4741</eissn><abstract>: Primary small cell neuroendocrine carcinoma of breast is a rare entity, with only case reports in literature. 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| ispartof | The breast journal, 2010-11, Vol.16 (6), p.647-651 |
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| language | eng |
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| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | Breast Neoplasms - pathology Carcinoma, Neuroendocrine - pathology Carcinoma, Small Cell - pathology Female Humans immunohistochemical Middle Aged neuroendocrine Positron-Emission Tomography Prognosis small cell Tomography, X-Ray Computed |
| title | An Unusual Case of Primary Small Cell Neuroendocrine Carcinoma of the Breast |
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