Blood and bronchoalveolar eosinophils in allergic subjects after segmental antigen challenge: Surface phenotype, density heterogeneity, and prostanoid production

Eosinophil infiltration into the airways has been implicated in the pathophysiology of asthma. To improve our understanding of the function of eosinophils in asthma, we have compared the phenotype and function of eosinophils obtained simultaneously from blood and bronchoalveolar lavage (BAL) of alle...

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Veröffentlicht in:	Journal of allergy and clinical immunology 1994-04, Vol.93 (4), p.725-734
Hauptverfasser:	Kroegel, Claus, Liu, Mark C., Hubbard, Walter C., Lichtenstein, Lawrence M., Bochner, Bruce S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Allergic diseases Antigens - immunology Antigens, Dermatophagoides Antigens, Surface - immunology Asthma - immunology Biological and medical sciences Bronchial Provocation Tests Bronchoalveolar eosinophils Bronchoalveolar Lavage Fluid - cytology Bronchoalveolar Lavage Fluid - immunology Cell Separation Centrifugation, Density Gradient Eosinophils - immunology Female Flow Cytometry Glycoproteins - immunology Humans hypodense eosinophils Immunopathology Immunophenotyping Leukocyte Count Male Medical sciences phenotype platelet activating factor Prostaglandins - biosynthesis prostanoid generation Respiratory and ent allergic diseases Rhinitis, Allergic, Perennial - immunology Up-Regulation
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