Bone marrow stromal cell blockade of human leukemic cell differentiation

Bone marrow (BM) stromal cell inhibition of leukemic cell differentiation was studied in cellular coculture experiments. In coculture, a significant percentage of cells from the human myeloid leukemic cell lines HL-60, PLB-985, and K562 adhere to fibroblastic KM-102 BM stromal cells. A sensitive two...

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Veröffentlicht in:	Blood 1994-04, Vol.83 (8), p.2221-2229
Hauptverfasser:	WEBER, M. C, TYKOCINSKI, M. L
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigens, CD - analysis Antigens, Differentiation, Myelomonocytic - analysis Biological and medical sciences Bone Marrow Cells CD18 Antigens Cell Communication Cell Differentiation Cells, Cultured Hematologic and hematopoietic diseases Humans Leukemia, Myeloid - pathology Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Lipopolysaccharide Receptors Medical sciences Stromal Cells - physiology
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