Age-related changes in the pharmacodynamics of verapamil

Age-related differences in the pharmacodynamics of numerous drugs are well documented. In this study, changes in the pharmacodynamics of verapamil were examined in anesthetized and unanesthetized puppies (6 weeks old) and adult dogs. Unanesthetized puppies and adult dogs were given verapamil (0.5 mg...

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Veröffentlicht in:	The American heart journal 1985-11, Vol.110 (5), p.981-985
Hauptverfasser:	Arnold, T.H., Vallner, J.J., Tackett, R.L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Aging Anesthesia Animals Antiarythmic agents Biological and medical sciences Blood Pressure - drug effects Cardiovascular system Dogs Electrocardiography Electrophysiology Heart Rate - drug effects Injections, Intravenous Kinetics Medical sciences Pharmacology. Drug treatments Time Factors Verapamil - administration & dosage Verapamil - metabolism
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