Rolipram, but not siguazodan or zaprinast, inhibits the excitatory noncholinergic neurotransmission in guinea-pig bronchi

Theophylline has been reported to inhibit excitatory noncholinergic but not cholinergic-neurotransmission in guinea-pig bronchi. As theophylline might exert this effect through an inhibition of phosphodiesterases (PDE), and since many types of PDE have now been described, the aim of this study was t...

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Veröffentlicht in:	The European respiratory journal 1994-02, Vol.7 (2), p.306-310
Hauptverfasser:	Qian, Y, Girard, V, Martin, CA, Molimard, M, Advenier, C
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Bronchi - drug effects Bronchi - innervation Electric Stimulation Female Guanidines - pharmacology Guinea Pigs In Vitro Techniques Male Medical sciences Nerve Fibers - drug effects Nerve Fibers - physiology Pharmacology. Drug treatments Phosphodiesterase Inhibitors - pharmacology Purinones - pharmacology Pyridazines - pharmacology Pyrrolidinones - pharmacology Respiratory system Rolipram Synaptic Transmission - drug effects
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