Isologous and heterologous platelet aggregation induced by tumor cells from three murine mammary gland adenocarcinomas with different metastatic abilities
The addition of neoplastic cells (NC) isolated from murine mammary gland adenocarcinomas having moderate and high metastatic ability on in vitro heparinized mice platelet rich plasma (PRP) induced platelet aggregation. One non-metastatic line did not induce aggregation. The aggregatory effect was no...
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Veröffentlicht in: | Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie 1994, Vol.45 (7), p.449-451 |
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container_title | Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie |
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creator | Pasqualini, Maria Eugenia Eynard, Aldo R. |
description | The addition of neoplastic cells (NC) isolated from murine mammary gland adenocarcinomas having moderate and high metastatic ability on
in vitro heparinized mice platelet rich plasma (PRP) induced platelet aggregation. One non-metastatic line did not induce aggregation. The aggregatory effect was not correlated with the metastatic abilities. None of the three types of tumors did cause aggregation on whole blood or PRP of rats. These adenocarcinomas seem to be suitable models to study
in vitro the interactions between platelets and tumor cells having metastatic and non-metastatic potentials. |
doi_str_mv | 10.1016/S0940-2993(11)80380-5 |
format | Article |
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in vitro heparinized mice platelet rich plasma (PRP) induced platelet aggregation. One non-metastatic line did not induce aggregation. The aggregatory effect was not correlated with the metastatic abilities. None of the three types of tumors did cause aggregation on whole blood or PRP of rats. These adenocarcinomas seem to be suitable models to study
in vitro the interactions between platelets and tumor cells having metastatic and non-metastatic potentials.</description><subject>Adenocarcinoma - pathology</subject><subject>Adenocarcinoma - physiopathology</subject><subject>Animal tumors. Experimental tumors</subject><subject>Animals</subject><subject>Biological and medical sciences</subject><subject>Experimental genital and mammary tumors</subject><subject>Female</subject><subject>Mammary gland adenocarcinoma, murine</subject><subject>Mammary Neoplasms, Experimental - pathology</subject><subject>Mammary Neoplasms, Experimental - physiopathology</subject><subject>Medical sciences</subject><subject>Metastases</subject><subject>Mice</subject><subject>Mice, Inbred BALB C</subject><subject>Neoplasm Metastasis</subject><subject>Platelet aggregation</subject><subject>Platelet Aggregation - physiology</subject><subject>Rats</subject><subject>Rats, Wistar</subject><subject>Tumor Cells, Cultured</subject><subject>Tumors</subject><issn>0940-2993</issn><issn>1618-1433</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1994</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkc9u1DAQxi0EKkvhESr5gBAcAnYcO8kJVRV_KlXiAJytiT3JGsX2YjugvgpPS9Jd9sppJM9vvvF8HyFXnL3ljKt3X1nfsKrue_Ga8zcdEx2r5COy44p3FW-EeEx2Z-QpeZbzD8Zq1kt-QS46rtpGdTvy5zbHOU5xyRSCpXssmP49HGYoOGOhME0JJyguBuqCXQxaOtzTsviYqMF5znRM0dOyT4jUL8mFtYD3kO7pNG_CYDFEA8m4ED1k-tuVPbVuHDFhKNRjgVzWDYbC4GZXHObn5MkIc8YXp3pJvn_88O3mc3X35dPtzfVdZQRrSgXMDCitHVjHVCcZN3zA3jQowa7yKMbWNlIqZiWOHSqDteR1y2U3AgOoxSV5ddQ9pPhzwVy0d3m7CgKuNuhWNY3oe7mC8giaFHNOOOpDctuNmjO9ZaIfMtGb4Zpz_ZCJ3uauTguWwaM9T51CWPsvT33IBuYxQTAunzGhaiZbtWLvjxiuZvxymHQ2DsMahktoirbR_ecjfwFIja4Q</recordid><startdate>1994</startdate><enddate>1994</enddate><creator>Pasqualini, Maria Eugenia</creator><creator>Eynard, Aldo R.</creator><general>Elsevier GmbH</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>1994</creationdate><title>Isologous and heterologous platelet aggregation induced by tumor cells from three murine mammary gland adenocarcinomas with different metastatic abilities</title><author>Pasqualini, Maria Eugenia ; Eynard, Aldo R.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c304t-a0cbe5ddb08068501c1be9c4e5adffee3f7d45560d5ef8e6ce25127158fa0aa23</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1994</creationdate><topic>Adenocarcinoma - pathology</topic><topic>Adenocarcinoma - physiopathology</topic><topic>Animal tumors. Experimental tumors</topic><topic>Animals</topic><topic>Biological and medical sciences</topic><topic>Experimental genital and mammary tumors</topic><topic>Female</topic><topic>Mammary gland adenocarcinoma, murine</topic><topic>Mammary Neoplasms, Experimental - pathology</topic><topic>Mammary Neoplasms, Experimental - physiopathology</topic><topic>Medical sciences</topic><topic>Metastases</topic><topic>Mice</topic><topic>Mice, Inbred BALB C</topic><topic>Neoplasm Metastasis</topic><topic>Platelet aggregation</topic><topic>Platelet Aggregation - physiology</topic><topic>Rats</topic><topic>Rats, Wistar</topic><topic>Tumor Cells, Cultured</topic><topic>Tumors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Pasqualini, Maria Eugenia</creatorcontrib><creatorcontrib>Eynard, Aldo R.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Pasqualini, Maria Eugenia</au><au>Eynard, Aldo R.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Isologous and heterologous platelet aggregation induced by tumor cells from three murine mammary gland adenocarcinomas with different metastatic abilities</atitle><jtitle>Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie</jtitle><addtitle>Exp Toxicol Pathol</addtitle><date>1994</date><risdate>1994</risdate><volume>45</volume><issue>7</issue><spage>449</spage><epage>451</epage><pages>449-451</pages><issn>0940-2993</issn><eissn>1618-1433</eissn><abstract>The addition of neoplastic cells (NC) isolated from murine mammary gland adenocarcinomas having moderate and high metastatic ability on
in vitro heparinized mice platelet rich plasma (PRP) induced platelet aggregation. One non-metastatic line did not induce aggregation. The aggregatory effect was not correlated with the metastatic abilities. None of the three types of tumors did cause aggregation on whole blood or PRP of rats. These adenocarcinomas seem to be suitable models to study
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subjects | Adenocarcinoma - pathology Adenocarcinoma - physiopathology Animal tumors. Experimental tumors Animals Biological and medical sciences Experimental genital and mammary tumors Female Mammary gland adenocarcinoma, murine Mammary Neoplasms, Experimental - pathology Mammary Neoplasms, Experimental - physiopathology Medical sciences Metastases Mice Mice, Inbred BALB C Neoplasm Metastasis Platelet aggregation Platelet Aggregation - physiology Rats Rats, Wistar Tumor Cells, Cultured Tumors |
title | Isologous and heterologous platelet aggregation induced by tumor cells from three murine mammary gland adenocarcinomas with different metastatic abilities |
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