To lower or not to lower? Making sense of the latest research on intensive glycaemic control and cardiovascular outcomes

Critical appraisal of the ACCORD, ADVANCE and UKPDS follow-up randomised controlled trials concerning the cardiovascular effects of lowering glucose levels to near-normal on patients with type 2 diabetes. Interventions, outcomes, the interpretation of results and the guidelines in use are discussed....

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Veröffentlicht in:Evidence-based nursing 2009-01, Vol.12 (1), p.4-6
Hauptverfasser: Sherifali, Diana, Punthakee, Zubin
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description Critical appraisal of the ACCORD, ADVANCE and UKPDS follow-up randomised controlled trials concerning the cardiovascular effects of lowering glucose levels to near-normal on patients with type 2 diabetes. Interventions, outcomes, the interpretation of results and the guidelines in use are discussed. [(BNI unique abstract)] 13 references
doi_str_mv 10.1136/ebn.12.1.4
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source MEDLINE; BMJ Journals - NESLi2
subjects Blood Glucose - drug effects
Cardiovascular Diseases - prevention & control
Clinical medicine
Clinical practice guidelines
Diabetes
Diabetes Mellitus, Type 2 - drug therapy
Diabetic Angiopathies - prevention & control
Glucose
Heart attacks
Hemoglobin
Humans
Hyperglycemia - drug therapy
Insulin
Intervention
Nursing
Treatment Outcome
title To lower or not to lower? Making sense of the latest research on intensive glycaemic control and cardiovascular outcomes
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