$Treatment of Refractory Disseminated Nontuberculous Mycobacterial Infection With Interferon Gamma: A Preliminary Report$

Treatment of Refractory Disseminated Nontuberculous Mycobacterial Infection With Interferon Gamma: A Preliminary Report

The importance of host factors in the susceptibility to mycobacterial infection has been suspected for over a century 1 . Patients with T-cell deficiencies, such as the acquired immunodeficiency syndrome 2 and idiopathic CD4+ T-lymphocytopenia, 3 – 6 and patients with abnormalities of monocyte or ma...

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Veröffentlicht in:	The New England journal of medicine 1994-05, Vol.330 (19), p.1348-1355
Hauptverfasser:	Holland, Steven M, Eisenstein, Eli M, Kuhns, Douglas B, Turner, Maria L, Fleisher, Thomas A, Strober, Warren, Gallin, John I
Format:	Artikel
Sprache:	eng
Schlagworte:	12-O-Tetradecanoylphorbol-13-acetate Acetic acid Adult AIDS/HIV Antibiotics. Antiinfectious agents. Antiparasitic agents Bacteremia - therapy Biological and medical sciences Biopsy CD4 antigen CD4-Positive T-Lymphocytes Cell culture Cell proliferation Chemotherapy Child, Preschool Cytokines Families & family life Family Health Fever Gene expression HIV Human immunodeficiency virus Humans Infections Infectious diseases Interferon-gamma - adverse effects Interferon-gamma - therapeutic use Ionomycin Laboratories Leprosy Leukocyte Count Leukocytes (mononuclear) Lymphocytes Lymphopenia Macrophages Male Medical sciences Middle Aged Miscellaneous. Antibiotics with multiple activities Monocytes Mycobacterium avium-intracellulare Infection - immunology Mycobacterium avium-intracellulare Infection - therapy Mycobacterium Infections, Nontuberculous - immunology Mycobacterium Infections, Nontuberculous - therapy Osteomyelitis - therapy Parasitic diseases Pathogens Peripheral blood Pharmacology. Drug treatments Radiography Skin Diseases, Bacterial - therapy Tuberculosis Tuberculosis, Pulmonary - therapy γ-Interferon
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