Exploring molecular diversity with combinatorial shape libraries

Surface technologies based upon selection of ligands from combinatorial libraries herald a revolution in molecular research and drug discovery. Molecular diversity is generated by random combinations of monomeric building blocks to form polymeric conformers that constitute ‘shape libraries’. The med...

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Veröffentlicht in:	Trends in biochemical sciences (Amsterdam. Regular ed.) 1994-02, Vol.19 (2), p.57-64
Hauptverfasser:	Kenan, Daniel J., Tsai, Donald E., Keene, Jack D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies - genetics Biological Evolution Gene Library Genetic Techniques Genetic Variation Ligands Nucleic Acids - genetics Oligonucleotides - chemistry Oligonucleotides - genetics Protein Binding RNA-Binding Proteins - genetics
Online-Zugang:	Volltext
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