Pamidronate for pain control in patients with malignant osteolytic bone disease: a prospective dose-effect study

In a prospective dose-escalation study tolerability and effectiveness of repeated infusions with intravenous pamidronate were investigated. A total of 80 patients with proven malignancy and pain due to osteolytic bone disease were enrolled. Doses of 30 mg, 45 mg, 60 mg and 90 mg pamidronate, given e...

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Veröffentlicht in:	Supportive care in cancer 1994-01, Vol.2 (1), p.61-65
Hauptverfasser:	Thürlimann, B, Morant, R, Jungi, W F, Radziwill, A
Format:	Artikel
Sprache:	eng
Schlagworte:	Activities of Daily Living Bone Neoplasms - physiopathology Bone Neoplasms - secondary Breast Neoplasms - pathology Diphosphonates - pharmacology Diphosphonates - therapeutic use Dose-Response Relationship, Drug Drug Administration Schedule Drug Evaluation Humans Infusions, Intravenous Linear Models Multiple Myeloma - pathology Pain - diagnosis Pain - drug therapy Pain - etiology Pain Measurement Prospective Studies Severity of Illness Index Time Factors
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