Late recurrence of testicular cancer
Late recurrence of nonseminomatous germ cell tumours of the testis is rare. The authors report on a 35-year-old man treated initially for embryonal cell carcinoma of the testis with metastases, who presented 12 years later with an increasing serum alpha-fetoprotein level and a biopsy-proven embryona...
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| Veröffentlicht in: | Canadian Journal of Surgery 1994-04, Vol.37 (2), p.165-167 |
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| container_title | Canadian Journal of Surgery |
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| creator | Embil, J M Weinerman, B H Pascoe, E A |
| description | Late recurrence of nonseminomatous germ cell tumours of the testis is rare. The authors report on a 35-year-old man treated initially for embryonal cell carcinoma of the testis with metastases, who presented 12 years later with an increasing serum alpha-fetoprotein level and a biopsy-proven embryonal cell cancer in the hilus of the left lung. Because the tumour was highly resistant to two separate courses of cis-platinum-based chemotherapy and one course of radiotherapy, surgical resection for salvage was carried out. The patient was free of disease 3.5 years after the second operation. The possible reasons for the occurrence of this highly resistant metastatic testicular cancer are discussed. They include a second primary tumour and malignant degeneration of the original tumour. In this patient the latter cause was the most plausible. |
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The authors report on a 35-year-old man treated initially for embryonal cell carcinoma of the testis with metastases, who presented 12 years later with an increasing serum alpha-fetoprotein level and a biopsy-proven embryonal cell cancer in the hilus of the left lung. Because the tumour was highly resistant to two separate courses of cis-platinum-based chemotherapy and one course of radiotherapy, surgical resection for salvage was carried out. The patient was free of disease 3.5 years after the second operation. The possible reasons for the occurrence of this highly resistant metastatic testicular cancer are discussed. They include a second primary tumour and malignant degeneration of the original tumour. In this patient the latter cause was the most plausible.</description><identifier>ISSN: 0008-428X</identifier><identifier>EISSN: 1488-2310</identifier><identifier>PMID: 8156473</identifier><identifier>CODEN: CJSUAX</identifier><language>eng</language><publisher>Canada: CMA Impact, Inc</publisher><subject>Adult ; Antineoplastic Combined Chemotherapy Protocols - therapeutic use ; Combined Modality Therapy ; Endodermal Sinus Tumor - pathology ; Endodermal Sinus Tumor - therapy ; Humans ; Lymphatic Metastasis ; Male ; Neoplasm Recurrence, Local - pathology ; Neoplasm Recurrence, Local - therapy ; Orchiectomy ; Postoperative Care ; Radiotherapy Dosage ; Salvage Therapy ; Testicular Neoplasms - pathology ; Testicular Neoplasms - therapy ; Time Factors</subject><ispartof>Canadian Journal of Surgery, 1994-04, Vol.37 (2), p.165-167</ispartof><rights>Copyright Canadian Medical Association Apr 1994</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/8156473$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Embil, J M</creatorcontrib><creatorcontrib>Weinerman, B H</creatorcontrib><creatorcontrib>Pascoe, E A</creatorcontrib><title>Late recurrence of testicular cancer</title><title>Canadian Journal of Surgery</title><addtitle>Can J Surg</addtitle><description>Late recurrence of nonseminomatous germ cell tumours of the testis is rare. 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| identifier | ISSN: 0008-428X |
| ispartof | Canadian Journal of Surgery, 1994-04, Vol.37 (2), p.165-167 |
| issn | 0008-428X 1488-2310 |
| language | eng |
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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | Adult Antineoplastic Combined Chemotherapy Protocols - therapeutic use Combined Modality Therapy Endodermal Sinus Tumor - pathology Endodermal Sinus Tumor - therapy Humans Lymphatic Metastasis Male Neoplasm Recurrence, Local - pathology Neoplasm Recurrence, Local - therapy Orchiectomy Postoperative Care Radiotherapy Dosage Salvage Therapy Testicular Neoplasms - pathology Testicular Neoplasms - therapy Time Factors |
| title | Late recurrence of testicular cancer |
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