A second promoter and enhancer element within the immunoglobulin heavy chain locus

The joining of immunoglobulin gene segments during B cell development consists of a tightly regulated series of rearrangement steps. A variety of experiments have suggested that transcription is involved in activating the locus as substrate for the V(D)J recombinase. Here, we have characterized a re...

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Veröffentlicht in:European journal of immunology 1994-04, Vol.24 (4), p.817-821
Hauptverfasser: Kottmann, Andreas H., Zevnik, Branko, Welte, Markus, Nielsen, Peter J., Köhler, Georges
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Sprache:eng
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