Photoaffinity labelling of the renal V2 vasopressin receptor: identification and enrichment of a vasopressin-binding subunit

To identify renal vasopressin receptor proteins, analogues of 1-deamino-vasopressin i.e. ([1-(2-mercapto)propionic acid]vasopressin, [Mpa1]VP) with photoreactive aryl-azido groups in position 4 and 8 of the vasopressin sequence were prepared. In the absence of ultraviolet light, these ligands exhibi...

Ausführliche Beschreibung