Features of the nutrient database and analysis system for the modification of Diet in Renal Disease Study

This article describes the features of the nutrient database and analysis system developed for the Modification of Diet in Renal Disease (MDRD) Study and outlines the development process itself, and example of tailoring a database and analysis system for a complex, long-term clinical trial. The MDRD...

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Veröffentlicht in:Controlled clinical trials 1994-02, Vol.15 (1), p.44-58
Hauptverfasser: Gillis, Bonnie P., Caggiula, Arlene W., Jones, Fran L., Maurer, Emil, Meehan, Rebecca M., Yamamoto, Monica E., the Modification of Diet in Renal Disease Study
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container_end_page 58
container_issue 1
container_start_page 44
container_title Controlled clinical trials
container_volume 15
creator Gillis, Bonnie P.
Caggiula, Arlene W.
Jones, Fran L.
Maurer, Emil
Meehan, Rebecca M.
Yamamoto, Monica E.
the Modification of Diet in Renal Disease Study
description This article describes the features of the nutrient database and analysis system developed for the Modification of Diet in Renal Disease (MDRD) Study and outlines the development process itself, and example of tailoring a database and analysis system for a complex, long-term clinical trial. The MDRD Study was a 15-center trial for men and women aged 18 to 70 years with chronic renal disease who were not on dialysis and who had not had a kidney transplant. The effects of three levels of protein and phosphorus intake and two levels of blood pressure management were assessed on rate of decline in kidney function. This paper describes the development, structure, contents, and application of the nutrient database and analysis system that was used to enter, analyze, and report the MDRD Study dietary data.
doi_str_mv 10.1016/0197-2456(94)90027-2
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subjects Adolescent
Adult
Aged
Blood Pressure - physiology
clinical trial
diet
dietary analysis
Dietary Proteins - administration & dosage
Energy Intake - physiology
Female
Glomerular Filtration Rate - physiology
Humans
Information Systems
Kidney Diseases - diet therapy
Kidney Diseases - physiopathology
Kidney Function Tests
Long-Term Care
Male
Middle Aged
nutrient calculation
Nutrient database
Nutritive Value
Phosphorus - administration & dosage
renal disease
Sodium Chloride, Dietary - administration & dosage
Software
title Features of the nutrient database and analysis system for the modification of Diet in Renal Disease Study
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