Sequence-specific DNA binding of the Epstein-Barr virus nuclear antigen (EBNA-1) to clustered sites in the plasmid maintenance region

Latently infected B lymphocytes continuously express an Epstein-Barr Virus nuclear antigen (EBNA-1) required in trans for maintenance of the plasmid state of the EBV genome. Filter binding assays and DNAase I footprinting analyses revealed that the carboxy-terminal domain of EBNA-1 protects binding...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Cell 1985-10, Vol.42 (3), p.859-868
Hauptverfasser:	Rawlins, Dan R., Milman, Gregory, Hayward, S.Diane, Hayward, Gary S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigens, Viral - genetics B-Lymphocytes - immunology Base Sequence Biological and medical sciences Cell Line Cloning, Molecular DNA Restriction Enzymes DNA, Viral - genetics Epstein-Barr virus Epstein-Barr Virus Nuclear Antigens Escherichia coli - genetics Fundamental and applied biological sciences. Psychology Gene expression Genes, Viral Herpesvirus 4, Human - genetics Herpesvirus 4, Human - immunology Humans Molecular and cellular biology Molecular genetics Plasmids Sequence Homology, Nucleic Acid
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!