Effects of propofol and thiopental on coronary blood flow and myocardial performance in an isolated rabbit heart

Some clinical and experimental studies suggest that propofol decreases myocardial contractility and relaxation, whereas others report preserved cardiac function. To investigate the effects of propofol on intrinsic contractility and relaxation, increasing concentrations of propofol were infused in is...

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Veröffentlicht in:	Anesthesiology (Philadelphia) 1994-03, Vol.80 (3), p.634-641
Hauptverfasser:	MOUREN, S, BARON, J.-F, ALBO, C, SZEKELY, B, ARTHAUD, M, VIARS, P
Format:	Artikel
Sprache:	eng
Schlagworte:	Anesthetics. Neuromuscular blocking agents Animals Biological and medical sciences Coronary Circulation - drug effects Electrolytes - blood Heart - drug effects Heart - physiology Heart Rate - drug effects Humans Hydrogen-Ion Concentration In Vitro Techniques Male Medical sciences Myocardial Contraction - drug effects Myocardium - metabolism Neuropharmacology Oxygen Consumption - drug effects Perfusion Pharmacology. Drug treatments Propofol - pharmacology Rabbits Thiopental - pharmacology Ventricular Function, Left - drug effects
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