The human glucagon receptor encoding gene: structure, cDNA sequence and chromosomal localization

Characterization of the human glucagon-receptor-encoding gene ( GGR) should provide a greater understanding of blood glucose regulation and may reveal a genetic basis for the pathogenesis of diabetes. A cDNA encoding a complete functional human glucagon receptor (GGR) was isolated from a liver cDNA...

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Veröffentlicht in:	Gene 1994-03, Vol.140 (2), p.203-209
Hauptverfasser:	Lok, Si, Kuijper, Joseph L., Jelinek, Laura J., Kramer, Janet M., Whitmore, Theodore E., Sprecher, Cindy A., Mathewes, Shannon, Grant, Francis J., Biggs, Shaula H., Rosenberg, Gary B., Sheppard, Paul O., O'Hara, Patrick J., Foster, Donald C., Kindsvogel, Wayne
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Base Sequence Biological and medical sciences Chromosome Mapping Chromosomes, Human, Pair 17 Cloning, Molecular DNA DNA, Complementary - genetics Fundamental and applied biological sciences. Psychology G-protein-coupled receptor Genes. Genome Glucagon - metabolism Humans introns Molecular and cellular biology Molecular genetics Molecular Sequence Data Polymerase Chain Reaction Rats Receptors, Glucagon - genetics Receptors, Glucagon - metabolism recombinant DNA Sequence Alignment Sequence Homology, Amino Acid Signal Transduction transmembrane domain
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