Quantitative evaluation of inflammation in biopsy specimens from idiopathically failing or irritable hearts: Experience in 80 pediatric and adult patients
The histologic criteria for the diagnosis of myocarditis on an endomyocardial biopsy specimen are troubled by varying institutional criteria and interobserver differences. A comprehensive approach to tissue evaluation including quantitative assessment of mononuclear cell populations enhances the acc...
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| Veröffentlicht in: | The American heart journal 1985-01, Vol.110 (4), p.713-720 |
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| container_end_page | 720 |
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| container_issue | 4 |
| container_start_page | 713 |
| container_title | The American heart journal |
| container_volume | 110 |
| creator | Cassling, Randal S. Linder, James Sears, Thomas D. Waller, Bruce F. Rogler, William C. Wilson, Janet E. Kugler, John D. Kay, David H. Dillon, James C. Slack, John D. McManus, Bruce M. |
| description | The histologic criteria for the diagnosis of myocarditis on an endomyocardial biopsy specimen are troubled by varying institutional criteria and interobserver differences. A comprehensive approach to tissue evaluation including quantitative assessment of mononuclear cell populations enhances the accuracy and the specificity of the morphologic diagnosis. Future efforts to characterize the infiltrating cell lines in inflammatory conditions of the heart will aid in the ultimate refinement of therapeutic efficacy. |
| doi_str_mv | 10.1016/0002-8703(85)90447-8 |
| format | Article |
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A comprehensive approach to tissue evaluation including quantitative assessment of mononuclear cell populations enhances the accuracy and the specificity of the morphologic diagnosis. Future efforts to characterize the infiltrating cell lines in inflammatory conditions of the heart will aid in the ultimate refinement of therapeutic efficacy.</description><subject>Adult</subject><subject>Biological and medical sciences</subject><subject>Biopsy</subject><subject>Cardiology. Vascular system</subject><subject>Cardiomyopathy, Dilated - pathology</subject><subject>Endocarditis - pathology</subject><subject>Endocardium - pathology</subject><subject>Female</subject><subject>Heart</subject><subject>Heart Failure - pathology</subject><subject>Heart failure, cardiogenic pulmonary edema, cardiac enlargement</subject><subject>Histocytochemistry</subject><subject>Humans</subject><subject>Immunoenzyme Techniques</subject><subject>Leukocytes - pathology</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Myocarditis - pathology</subject><subject>Myocardium - pathology</subject><issn>0002-8703</issn><issn>1097-6744</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1985</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kc9u1DAQhyNEVZbCG4DkA0JwCNiJ49g9IKGq0EqVEBKcLccZ00GOE2xn1X0VnhZvd7VHTv4z3_xkf1NVrxj9wCgTHymlTS172r6T3XtFOe9r-aTaMKr6WvScP602J-RZ9Tyl3-UoGinOq_NWUdYzvqn-fl9NyJhNxi0Q2Bq_lu0cyOwIBufNNB3OGMiA85J2JC1gcYKQiIvzRHAs1ybfozXe74gz6DH8InMkGGMJHjyQezAxp0ty_bBARAgW9nmSkgVGNDmiJSaMxIyrz6SEFSSnF9WZMz7By-N6Uf38cv3j6qa--_b19urzXW0563KthGF9M_SiZa00fBACgHWCjRIapuwgrCrfLsY4g0514BrXNeBoMaTaVrbtRfX2kLvE-c8KKesJkwXvTYB5TboXnKqu5wXkB9DGOaUITi8RJxN3mlG9H4ne-9Z731p2-nEkWpa218f8dZhgPDUdZ1Dqb451k4pDF02wmE6YamTbCVWwTwcMiostQtTJPqocMYLNepzx_-_4Bzttqao</recordid><startdate>19850101</startdate><enddate>19850101</enddate><creator>Cassling, Randal S.</creator><creator>Linder, James</creator><creator>Sears, Thomas D.</creator><creator>Waller, Bruce F.</creator><creator>Rogler, William C.</creator><creator>Wilson, Janet E.</creator><creator>Kugler, John D.</creator><creator>Kay, David H.</creator><creator>Dillon, James C.</creator><creator>Slack, John D.</creator><creator>McManus, Bruce M.</creator><general>Mosby, Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19850101</creationdate><title>Quantitative evaluation of inflammation in biopsy specimens from idiopathically failing or irritable hearts: Experience in 80 pediatric and adult patients</title><author>Cassling, Randal S. ; Linder, James ; Sears, Thomas D. ; Waller, Bruce F. ; Rogler, William C. ; Wilson, Janet E. ; Kugler, John D. ; Kay, David H. ; Dillon, James C. ; Slack, John D. ; McManus, Bruce M.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c415t-96a172b763138a4b66ee1561d8e219cb6c900610141e595ef2f52ef0744933833</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1985</creationdate><topic>Adult</topic><topic>Biological and medical sciences</topic><topic>Biopsy</topic><topic>Cardiology. 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| fulltext | fulltext |
| identifier | ISSN: 0002-8703 |
| ispartof | The American heart journal, 1985-01, Vol.110 (4), p.713-720 |
| issn | 0002-8703 1097-6744 |
| language | eng |
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| source | MEDLINE; Access via ScienceDirect (Elsevier) |
| subjects | Adult Biological and medical sciences Biopsy Cardiology. Vascular system Cardiomyopathy, Dilated - pathology Endocarditis - pathology Endocardium - pathology Female Heart Heart Failure - pathology Heart failure, cardiogenic pulmonary edema, cardiac enlargement Histocytochemistry Humans Immunoenzyme Techniques Leukocytes - pathology Male Medical sciences Middle Aged Myocarditis - pathology Myocardium - pathology |
| title | Quantitative evaluation of inflammation in biopsy specimens from idiopathically failing or irritable hearts: Experience in 80 pediatric and adult patients |
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