Adherence to HIV combination therapy
The emergence of drug-resistant strains of HIV virus and treatment failure can result from non-adherence to antiretroviral therapy. While non-adherence to therapy is not a new issue or specific to HIV/AIDS, it has received renewed attention because of the complicated combination treatment regimens b...
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| Veröffentlicht in: | Social science & medicine (1982) 2000-06, Vol.50 (11), p.1599-1605 |
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| container_title | Social science & medicine (1982) |
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| creator | Chesney, Margaret A Morin, Michel Sherr, Lorraine |
| description | The emergence of drug-resistant strains of HIV virus and treatment failure can result from non-adherence to antiretroviral therapy. While non-adherence to therapy is not a new issue or specific to HIV/AIDS, it has received renewed attention because of the complicated combination treatment regimens being prescribed. This paper reviews the relevant background literature on the contributions of social and behavioural science to non-adherence to HIV medications. Data indicating problems with adherence prior to combination therapy are reported. Despite limitations, even self-report assessments have already succeeded in showing that adherence to combination therapy is significantly related to HIV viral load. Recent research data are discussed. Implications of findings for counselling patients to increase their adherence are presented. |
| doi_str_mv | 10.1016/S0277-9536(99)00468-2 |
| format | Article |
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While non-adherence to therapy is not a new issue or specific to HIV/AIDS, it has received renewed attention because of the complicated combination treatment regimens being prescribed. This paper reviews the relevant background literature on the contributions of social and behavioural science to non-adherence to HIV medications. Data indicating problems with adherence prior to combination therapy are reported. Despite limitations, even self-report assessments have already succeeded in showing that adherence to combination therapy is significantly related to HIV viral load. Recent research data are discussed. 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While non-adherence to therapy is not a new issue or specific to HIV/AIDS, it has received renewed attention because of the complicated combination treatment regimens being prescribed. This paper reviews the relevant background literature on the contributions of social and behavioural science to non-adherence to HIV medications. Data indicating problems with adherence prior to combination therapy are reported. Despite limitations, even self-report assessments have already succeeded in showing that adherence to combination therapy is significantly related to HIV viral load. Recent research data are discussed. Implications of findings for counselling patients to increase their adherence are presented.</description><subject>Acquired Immune Deficiency Syndrome</subject><subject>Adherence</subject><subject>AIDS</subject><subject>AIDS/HIV</subject><subject>Anti-HIV Agents - therapeutic use</subject><subject>Combination therapy</subject><subject>Counselling</subject><subject>Drug Resistance, Microbial</subject><subject>Drug therapy</subject><subject>Drug Therapy, Combination</subject><subject>Drugs</subject><subject>HIV</subject><subject>HIV - drug effects</subject><subject>HIV Infections - drug therapy</subject><subject>HIV Infections - psychology</subject><subject>HIV Infections - virology</subject><subject>Human immunodeficiency virus</subject><subject>Humans</subject><subject>Illness</subject><subject>Life Style</subject><subject>Medications</subject><subject>Mental health</subject><subject>Patient Compliance</subject><subject>Sociobehavioural research</subject><subject>Treatment</subject><subject>Treatment Compliance</subject><subject>Treatment Methods</subject><issn>0277-9536</issn><issn>1873-5347</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2000</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BHHNA</sourceid><sourceid>7QJ</sourceid><recordid>eNqN0ktLYzEUB_AgI1ofH8GhDOJjccdz8s5qkKJTQXAxM25DkpviLe29neRW6Lef1IqIi6mrBPI7JyTnT8gJwncElFe_gCpVGcHkhTGXAFzqiu6QAWrFKsG4-kIGb2SfHOQ8BQAEzfbIPoIywkg5IKfX9VNMsQ1x2HfD8d3jMHRz37Sub7p22Jczt1gdkd2Jm-V4_Loekj-3N79H4-r-4efd6Pq-CqVZXwVPhQMWUHshMDo02kevpULOjKjdhIHgzimQjnpelyMRBLKywdp49OyQnG_6LlL3dxlzb-dNDnE2c23sltkqycFQjqLIs__L8lAhDWyFEiU3kopPQGGQod4KheIogZqtkGktKQUs8NsHOO2WqS0_bSkrgwVtaEFig0Lqck5xYhepmbu0sgh2nQj7kgi7Hrc1xr4kwq7rvr42X_p5rN9VbSJQwI8NiGWyz01MNodmHYi6STH0tu6aLVf8A8Hgwag</recordid><startdate>20000601</startdate><enddate>20000601</enddate><creator>Chesney, Margaret A</creator><creator>Morin, Michel</creator><creator>Sherr, Lorraine</creator><general>Elsevier Ltd</general><general>Pergamon Press Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7U3</scope><scope>7U4</scope><scope>8BJ</scope><scope>BHHNA</scope><scope>DWI</scope><scope>FQK</scope><scope>JBE</scope><scope>K9.</scope><scope>WZK</scope><scope>7QJ</scope><scope>7X8</scope><scope>ASE</scope><scope>FPQ</scope><scope>K6X</scope></search><sort><creationdate>20000601</creationdate><title>Adherence to HIV combination therapy</title><author>Chesney, Margaret A ; Morin, Michel ; Sherr, Lorraine</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c596t-cb25a03c18b551ea198beb86714395daf3054aa706a2b4deb85c513deb1d9b1b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2000</creationdate><topic>Acquired Immune Deficiency Syndrome</topic><topic>Adherence</topic><topic>AIDS</topic><topic>AIDS/HIV</topic><topic>Anti-HIV Agents - therapeutic use</topic><topic>Combination therapy</topic><topic>Counselling</topic><topic>Drug Resistance, Microbial</topic><topic>Drug therapy</topic><topic>Drug Therapy, Combination</topic><topic>Drugs</topic><topic>HIV</topic><topic>HIV - drug effects</topic><topic>HIV Infections - drug therapy</topic><topic>HIV Infections - psychology</topic><topic>HIV Infections - virology</topic><topic>Human immunodeficiency virus</topic><topic>Humans</topic><topic>Illness</topic><topic>Life Style</topic><topic>Medications</topic><topic>Mental health</topic><topic>Patient Compliance</topic><topic>Sociobehavioural research</topic><topic>Treatment</topic><topic>Treatment Compliance</topic><topic>Treatment Methods</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Chesney, Margaret A</creatorcontrib><creatorcontrib>Morin, Michel</creatorcontrib><creatorcontrib>Sherr, Lorraine</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Social Services Abstracts</collection><collection>Sociological Abstracts (pre-2017)</collection><collection>International Bibliography of the Social Sciences (IBSS)</collection><collection>Sociological Abstracts</collection><collection>Sociological Abstracts</collection><collection>International Bibliography of the Social Sciences</collection><collection>International Bibliography of the Social Sciences</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Sociological Abstracts (Ovid)</collection><collection>Applied Social Sciences Index & Abstracts (ASSIA)</collection><collection>MEDLINE - Academic</collection><collection>British Nursing Index</collection><collection>British Nursing Index (BNI) (1985 to Present)</collection><collection>British Nursing Index</collection><jtitle>Social science & medicine (1982)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Chesney, Margaret A</au><au>Morin, Michel</au><au>Sherr, Lorraine</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Adherence to HIV combination therapy</atitle><jtitle>Social science & medicine (1982)</jtitle><addtitle>Soc Sci Med</addtitle><date>2000-06-01</date><risdate>2000</risdate><volume>50</volume><issue>11</issue><spage>1599</spage><epage>1605</epage><pages>1599-1605</pages><issn>0277-9536</issn><eissn>1873-5347</eissn><coden>SSMDEP</coden><abstract>The emergence of drug-resistant strains of HIV virus and treatment failure can result from non-adherence to antiretroviral therapy. While non-adherence to therapy is not a new issue or specific to HIV/AIDS, it has received renewed attention because of the complicated combination treatment regimens being prescribed. This paper reviews the relevant background literature on the contributions of social and behavioural science to non-adherence to HIV medications. Data indicating problems with adherence prior to combination therapy are reported. Despite limitations, even self-report assessments have already succeeded in showing that adherence to combination therapy is significantly related to HIV viral load. Recent research data are discussed. Implications of findings for counselling patients to increase their adherence are presented.</abstract><cop>England</cop><pub>Elsevier Ltd</pub><pmid>10795966</pmid><doi>10.1016/S0277-9536(99)00468-2</doi><tpages>7</tpages></addata></record> |
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| subjects | Acquired Immune Deficiency Syndrome Adherence AIDS AIDS/HIV Anti-HIV Agents - therapeutic use Combination therapy Counselling Drug Resistance, Microbial Drug therapy Drug Therapy, Combination Drugs HIV HIV - drug effects HIV Infections - drug therapy HIV Infections - psychology HIV Infections - virology Human immunodeficiency virus Humans Illness Life Style Medications Mental health Patient Compliance Sociobehavioural research Treatment Treatment Compliance Treatment Methods |
| title | Adherence to HIV combination therapy |
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