Use of COMBINATION ANTIRETROVIRAL THERAPY In Pregnant Women With HIV Disease

Important advances in human immunodeficiency virus (HIV) medicine have brought about numerous changes in the clinical care of HIV-infected individuals. The availability of protease inhibitors to treat HIV infection, the introduction of HIV-RNA polymerase chain reaction viral load tests to monitor re...

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Veröffentlicht in:MCN, the American journal of maternal child nursing the American journal of maternal child nursing, 1998-11, Vol.23 (6), p.307-312
Hauptverfasser: Newshan, Gayle, Hoyt, Mary Jo
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description Important advances in human immunodeficiency virus (HIV) medicine have brought about numerous changes in the clinical care of HIV-infected individuals. The availability of protease inhibitors to treat HIV infection, the introduction of HIV-RNA polymerase chain reaction viral load tests to monitor responses to therapy, and the greater clinical benefit offered by combination highly active antiretroviral therapy (HAART) over monotherapy have dramatically decreased morbidity and mortality rates. The safety and efficacy of HAART has not been proved in pregnant women with HIV, although withholding HAART in HIV-infected women because of pregnancy is not recommended. This article presents an overview of important clinical issues relevant to the use of combination antiretroviral therapy in pregnancy.
doi_str_mv 10.1097/00005721-199811000-00006
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subjects Adult
AIDS/HIV
Anti-HIV Agents - therapeutic use
Drug Therapy, Combination
Female
HIV Infections - drug therapy
HIV Protease Inhibitors - therapeutic use
Humans
Infectious Disease Transmission, Vertical - prevention & control
Nursing
Pregnancy
Pregnancy Complications, Infectious - drug therapy
Pregnancy Complications, Infectious - virology
title Use of COMBINATION ANTIRETROVIRAL THERAPY In Pregnant Women With HIV Disease
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