Sustained-Release Oral Delivery of Theophylline by Use of Polyvinyl Alcohol and Polyvinyl Alcohol-Methyl Acrylate Polymers

□ Crystalline polyvinyl alcohol (PVA) polymer and low- crystallinity polyvinyl alcohol-methyl acrylate copolymer (PVA-MA) were examined as sustained-release tablet excipients with theophylline as a model drug. By blending of different proportions of the crystalline polymer and the low-crystallinity...

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Veröffentlicht in:	Journal of pharmaceutical sciences 1994-01, Vol.83 (1), p.104-106
Hauptverfasser:	Diluccio, Robert C., Hussain, Munir A., Coffin-Beach, David, Torosian, George, Shefter, Eli, Hurwitz, Arthur R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Absorption Acrylates Administration, Oral Animals Biological and medical sciences Crystallization Delayed-Action Preparations Dogs Female Medical sciences Pharmacology. Drug treatments Polyvinyl Alcohol Respiratory system Theophylline - administration & dosage Theophylline - pharmacokinetics
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