Human, Mouse, and Rat Calnexin cDNA Cloning: Identification of Potential Calcium Binding Motifs and Gene Localization to Human Chromosome 5

Calnexin is a 90-kDa integral membrane protein of the endoplasmic reticulum (ER). Calnexin binds Ca2+ and may function as a chaperone in the transition of proteins from the ER to the outer cellular membrane. We have purified human calnexin in association with the human interferon-gamma receptor and...

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Veröffentlicht in:	Biochemistry (Easton) 1994-03, Vol.33 (11), p.3229-3236
Hauptverfasser:	Tjoelker, Larry W, Seyfried, Christine E, Eddy, Roger L, Byers, Mary G, Shows, Thomas B, Calderon, Jesus, Schreiber, Robert B, Gray, Patrick W
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Analytical, structural and metabolic biochemistry Animals Base Sequence Binding and carrier proteins Binding Sites Biological and medical sciences Calcium - metabolism Calcium-Binding Proteins - chemistry Calcium-Binding Proteins - genetics Calcium-Binding Proteins - metabolism Calnexin Chromosome Mapping Chromosomes, Human, Pair 5 Cloning, Molecular DNA, Complementary - chemistry DNA, Complementary - genetics Female Fundamental and applied biological sciences. Psychology Glutathione Transferase - genetics Humans Interferon gamma Receptor Mice Molecular Sequence Data Peptide Fragments - chemistry Peptide Fragments - genetics Peptide Fragments - metabolism Placenta - chemistry Proteins Rats Receptors, Interferon - metabolism Recombinant Fusion Proteins - chemistry Recombinant Fusion Proteins - metabolism Sequence Homology
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