Little or No Expression of the Cholecystokinin-A Receptor Gene in the Pancreas of Diabetic Rats (Otsuka Long-Evans Tokushima Fatty=OLETF Rats)

Expression of the CCK-A receptor gene in the pancreas and pancreatic exocrine function was examined in diabetic model rats (OLETF) at 5 wks of age. Little or no CCK-A receptor was detected in the pancreas of OLETF rats. Pancreatic exocrine function in response to exogenous CCK and to bile-pancreatic...

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Veröffentlicht in:	Biochemical and biophysical research communications 1994-03, Vol.199 (2), p.482-488
Hauptverfasser:	Funakoshi, A., Miyasaka, K., Jimi, A., Kawanai, T., Takata, Y., Kono, A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigens, Neoplasm Base Sequence Biomarkers, Tumor Blotting, Northern Cholecystokinin - physiology Cytoplasmic Granules - pathology Cytoplasmic Granules - ultrastructure DIABETE DIABETES Diabetes Mellitus, Type 2 - genetics Diabetes Mellitus, Type 2 - metabolism Diabetes Mellitus, Type 2 - physiopathology EXPRESION GENICA EXPRESSION DES GENES GENE Gene Expression GENES HORMONAS GASTROINTESTINALES HORMONE GASTROINTESTINALE Lectins, C-Type Male Microscopy, Electron MODELE MODELOS Molecular Sequence Data Oligonucleotide Probes PANCREAS Pancreas - metabolism Pancreas - pathology Pancreas - ultrastructure Pancreatic Juice - secretion Pancreatitis-Associated Proteins Protein Biosynthesis RAT RATA Rats Rats, Mutant Strains RECEPTEUR D'HORMONE Receptor, Cholecystokinin A RECEPTORES DE HORMONAS Receptors, Cholecystokinin - biosynthesis RNA, Messenger - analysis RNA, Messenger - biosynthesis Sincalide - pharmacology
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