Direct determination of mitoxantrone in plasma by high performance liquid chromatography using an automatic precolumn-switching system as sample clean-up procedure

A high‐performance liquid chromatography method which uses direct injection and a column‐switching valve for determination of mitoxantrone in plasma is described. After addition of internal standard, plasma was deproteinized by adding 5‐sulphosalicylic acid reagent. The supernatant was injected onto...

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Veröffentlicht in:Biomedical chromatography 1994-01, Vol.8 (1), p.37-41
Hauptverfasser: Catalin, Jacques, Peloux, Anne F., Coloma, Fabrice, Payet, Brigitte, Lacarelle, Bruno, Cano, Jean P., Just-Landi, Sylvaine
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Sprache:eng
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