Multiple Brain Infarction and Hemorrhage by Nonbacterial Thrombotic Endocarditis in Occult Lung Cancer: A Case Report
A fifty-four-year-old woman died from multiple brain infarction and hemor rhage in the bilateral cerebrum, cerebellum, and brainstem, with renal infarc tion. She developed hematuria and transient blindness sixteen days before admission. Low-grade fever, heart murmur, and aortic valve vegetation on u...
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Veröffentlicht in: | Angiology 1994-02, Vol.45 (2), p.161-166 |
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creator | Fujishima, Shinichiro Okada, Yasushi Irie, Katsumi Kitazono, Takanari Saku, Yoshisuke Utsunomiya, Hidetsuna Sugihara, Shigetaka Sadoshima, Seizo Fujishima, Masatoshi |
description | A fifty-four-year-old woman died from multiple brain infarction and hemor rhage in the bilateral cerebrum, cerebellum, and brainstem, with renal infarc tion. She developed hematuria and transient blindness sixteen days before admission. Low-grade fever, heart murmur, and aortic valve vegetation on ul trasonic cardiography suggested infectious endocarditis. Autopsy study re vealed occult adenocarcinoma in the lung and nonbacterial thrombotic endocarditis, but infective endocarditis was not histologically confirmed. The patient was considered to be a rare case of nonbacterial thrombotic endocarditis who developed multiple small infarctions mainly in the brainstem and cerebel lum. Nonbacterial thrombotic endocarditis seems to be still an important dis ease as the embolic source, even if cryptic, of systemic thromboembolism. |
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She developed hematuria and transient blindness sixteen days before admission. Low-grade fever, heart murmur, and aortic valve vegetation on ul trasonic cardiography suggested infectious endocarditis. Autopsy study re vealed occult adenocarcinoma in the lung and nonbacterial thrombotic endocarditis, but infective endocarditis was not histologically confirmed. The patient was considered to be a rare case of nonbacterial thrombotic endocarditis who developed multiple small infarctions mainly in the brainstem and cerebel lum. Nonbacterial thrombotic endocarditis seems to be still an important dis ease as the embolic source, even if cryptic, of systemic thromboembolism.</description><identifier>ISSN: 0003-3197</identifier><identifier>EISSN: 1940-1574</identifier><identifier>DOI: 10.1177/000331979404500213</identifier><identifier>PMID: 8129193</identifier><identifier>CODEN: ANGIAB</identifier><language>eng</language><publisher>Thousand Oaks, CA: SAGE Publications</publisher><subject>Adenocarcinoma - complications ; Biological and medical sciences ; Blindness - etiology ; Cerebral Hemorrhage - etiology ; Cerebral Infarction - etiology ; Coronary Thrombosis - complications ; Coronary Thrombosis - etiology ; Diagnosis, Differential ; Echocardiography ; Endocarditis - complications ; Endocarditis - etiology ; Female ; Hematuria - etiology ; Humans ; Infarction - complications ; Infarction - etiology ; Kidney - blood supply ; Lung Neoplasms - complications ; Magnetic Resonance Imaging ; Medical sciences ; Middle Aged ; Pneumology ; Thromboembolism - complications ; Thromboembolism - etiology ; Tumors of the respiratory system and mediastinum</subject><ispartof>Angiology, 1994-02, Vol.45 (2), p.161-166</ispartof><rights>1994 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c349t-cab0e5d73efe24b86a68bb5e3eb747adc7c7bdb3eb05db24097299de9285f8363</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://journals.sagepub.com/doi/pdf/10.1177/000331979404500213$$EPDF$$P50$$Gsage$$H</linktopdf><linktohtml>$$Uhttps://journals.sagepub.com/doi/10.1177/000331979404500213$$EHTML$$P50$$Gsage$$H</linktohtml><link.rule.ids>315,781,785,21824,27929,27930,43626,43627</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=3938564$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/8129193$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Fujishima, Shinichiro</creatorcontrib><creatorcontrib>Okada, Yasushi</creatorcontrib><creatorcontrib>Irie, Katsumi</creatorcontrib><creatorcontrib>Kitazono, Takanari</creatorcontrib><creatorcontrib>Saku, Yoshisuke</creatorcontrib><creatorcontrib>Utsunomiya, Hidetsuna</creatorcontrib><creatorcontrib>Sugihara, Shigetaka</creatorcontrib><creatorcontrib>Sadoshima, Seizo</creatorcontrib><creatorcontrib>Fujishima, Masatoshi</creatorcontrib><title>Multiple Brain Infarction and Hemorrhage by Nonbacterial Thrombotic Endocarditis in Occult Lung Cancer: A Case Report</title><title>Angiology</title><addtitle>Angiology</addtitle><description>A fifty-four-year-old woman died from multiple brain infarction and hemor rhage in the bilateral cerebrum, cerebellum, and brainstem, with renal infarc tion. She developed hematuria and transient blindness sixteen days before admission. Low-grade fever, heart murmur, and aortic valve vegetation on ul trasonic cardiography suggested infectious endocarditis. Autopsy study re vealed occult adenocarcinoma in the lung and nonbacterial thrombotic endocarditis, but infective endocarditis was not histologically confirmed. The patient was considered to be a rare case of nonbacterial thrombotic endocarditis who developed multiple small infarctions mainly in the brainstem and cerebel lum. Nonbacterial thrombotic endocarditis seems to be still an important dis ease as the embolic source, even if cryptic, of systemic thromboembolism.</description><subject>Adenocarcinoma - complications</subject><subject>Biological and medical sciences</subject><subject>Blindness - etiology</subject><subject>Cerebral Hemorrhage - etiology</subject><subject>Cerebral Infarction - etiology</subject><subject>Coronary Thrombosis - complications</subject><subject>Coronary Thrombosis - etiology</subject><subject>Diagnosis, Differential</subject><subject>Echocardiography</subject><subject>Endocarditis - complications</subject><subject>Endocarditis - etiology</subject><subject>Female</subject><subject>Hematuria - etiology</subject><subject>Humans</subject><subject>Infarction - complications</subject><subject>Infarction - etiology</subject><subject>Kidney - blood supply</subject><subject>Lung Neoplasms - complications</subject><subject>Magnetic Resonance Imaging</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Pneumology</subject><subject>Thromboembolism - complications</subject><subject>Thromboembolism - etiology</subject><subject>Tumors of the respiratory system and mediastinum</subject><issn>0003-3197</issn><issn>1940-1574</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1994</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkUtrGzEUhUVocJ3HHwgUtCjdTaPHaDRatsZ5gNNs0vWgxx1HYUZypZlF_n1lbLwppKvL4X73XDgHoRtKvlMq5S0hhHOqpKpJLQhhlJ-hJS2qokLWn9ByD1R74jO6yPmtSEFJs0CLljJFFV-i_mkeJr8bAP9M2gf8GHqd7ORjwDo4_ABjTOlVbwGbd_wrBqPtBMnrAb-8pjiaOHmL18FFq5Pzk8-4mDxbW1zxZg5bvNLBQrpC570eMlwf5yX6fbd-WT1Um-f7x9WPTWV5rabKakNAOMmhB1abttFNa4wADkbWUjsrrTTOFEmEM6wmSjKlHCjWir7lDb9E3w6-uxT_zJCnbvTZwjDoAHHOnWy4EpyS_4KMkJYJIQrIDqBNMecEfbdLftTpvaOk27fQ_dtCOfpydJ_NCO50coy97L8e9zpbPfSphOTzCeOKt6KpC3Z7wHIpoHuLcwolvI8e_wWbU5zQ</recordid><startdate>19940201</startdate><enddate>19940201</enddate><creator>Fujishima, Shinichiro</creator><creator>Okada, Yasushi</creator><creator>Irie, Katsumi</creator><creator>Kitazono, Takanari</creator><creator>Saku, Yoshisuke</creator><creator>Utsunomiya, Hidetsuna</creator><creator>Sugihara, Shigetaka</creator><creator>Sadoshima, Seizo</creator><creator>Fujishima, Masatoshi</creator><general>SAGE Publications</general><general>Westminster</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TK</scope><scope>7X8</scope></search><sort><creationdate>19940201</creationdate><title>Multiple Brain Infarction and Hemorrhage by Nonbacterial Thrombotic Endocarditis in Occult Lung Cancer</title><author>Fujishima, Shinichiro ; Okada, Yasushi ; Irie, Katsumi ; Kitazono, Takanari ; Saku, Yoshisuke ; Utsunomiya, Hidetsuna ; Sugihara, Shigetaka ; Sadoshima, Seizo ; Fujishima, Masatoshi</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c349t-cab0e5d73efe24b86a68bb5e3eb747adc7c7bdb3eb05db24097299de9285f8363</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1994</creationdate><topic>Adenocarcinoma - complications</topic><topic>Biological and medical sciences</topic><topic>Blindness - etiology</topic><topic>Cerebral Hemorrhage - etiology</topic><topic>Cerebral Infarction - etiology</topic><topic>Coronary Thrombosis - complications</topic><topic>Coronary Thrombosis - etiology</topic><topic>Diagnosis, Differential</topic><topic>Echocardiography</topic><topic>Endocarditis - complications</topic><topic>Endocarditis - etiology</topic><topic>Female</topic><topic>Hematuria - etiology</topic><topic>Humans</topic><topic>Infarction - complications</topic><topic>Infarction - etiology</topic><topic>Kidney - blood supply</topic><topic>Lung Neoplasms - complications</topic><topic>Magnetic Resonance Imaging</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Pneumology</topic><topic>Thromboembolism - complications</topic><topic>Thromboembolism - etiology</topic><topic>Tumors of the respiratory system and mediastinum</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Fujishima, Shinichiro</creatorcontrib><creatorcontrib>Okada, Yasushi</creatorcontrib><creatorcontrib>Irie, Katsumi</creatorcontrib><creatorcontrib>Kitazono, Takanari</creatorcontrib><creatorcontrib>Saku, Yoshisuke</creatorcontrib><creatorcontrib>Utsunomiya, Hidetsuna</creatorcontrib><creatorcontrib>Sugihara, Shigetaka</creatorcontrib><creatorcontrib>Sadoshima, Seizo</creatorcontrib><creatorcontrib>Fujishima, Masatoshi</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Neurosciences Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Angiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Fujishima, Shinichiro</au><au>Okada, Yasushi</au><au>Irie, Katsumi</au><au>Kitazono, Takanari</au><au>Saku, Yoshisuke</au><au>Utsunomiya, Hidetsuna</au><au>Sugihara, Shigetaka</au><au>Sadoshima, Seizo</au><au>Fujishima, Masatoshi</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Multiple Brain Infarction and Hemorrhage by Nonbacterial Thrombotic Endocarditis in Occult Lung Cancer: A Case Report</atitle><jtitle>Angiology</jtitle><addtitle>Angiology</addtitle><date>1994-02-01</date><risdate>1994</risdate><volume>45</volume><issue>2</issue><spage>161</spage><epage>166</epage><pages>161-166</pages><issn>0003-3197</issn><eissn>1940-1574</eissn><coden>ANGIAB</coden><abstract>A fifty-four-year-old woman died from multiple brain infarction and hemor rhage in the bilateral cerebrum, cerebellum, and brainstem, with renal infarc tion. She developed hematuria and transient blindness sixteen days before admission. Low-grade fever, heart murmur, and aortic valve vegetation on ul trasonic cardiography suggested infectious endocarditis. Autopsy study re vealed occult adenocarcinoma in the lung and nonbacterial thrombotic endocarditis, but infective endocarditis was not histologically confirmed. The patient was considered to be a rare case of nonbacterial thrombotic endocarditis who developed multiple small infarctions mainly in the brainstem and cerebel lum. Nonbacterial thrombotic endocarditis seems to be still an important dis ease as the embolic source, even if cryptic, of systemic thromboembolism.</abstract><cop>Thousand Oaks, CA</cop><pub>SAGE Publications</pub><pmid>8129193</pmid><doi>10.1177/000331979404500213</doi><tpages>6</tpages></addata></record> |
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subjects | Adenocarcinoma - complications Biological and medical sciences Blindness - etiology Cerebral Hemorrhage - etiology Cerebral Infarction - etiology Coronary Thrombosis - complications Coronary Thrombosis - etiology Diagnosis, Differential Echocardiography Endocarditis - complications Endocarditis - etiology Female Hematuria - etiology Humans Infarction - complications Infarction - etiology Kidney - blood supply Lung Neoplasms - complications Magnetic Resonance Imaging Medical sciences Middle Aged Pneumology Thromboembolism - complications Thromboembolism - etiology Tumors of the respiratory system and mediastinum |
title | Multiple Brain Infarction and Hemorrhage by Nonbacterial Thrombotic Endocarditis in Occult Lung Cancer: A Case Report |
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