Multiple Brain Infarction and Hemorrhage by Nonbacterial Thrombotic Endocarditis in Occult Lung Cancer: A Case Report

A fifty-four-year-old woman died from multiple brain infarction and hemor rhage in the bilateral cerebrum, cerebellum, and brainstem, with renal infarc tion. She developed hematuria and transient blindness sixteen days before admission. Low-grade fever, heart murmur, and aortic valve vegetation on u...

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Veröffentlicht in:Angiology 1994-02, Vol.45 (2), p.161-166
Hauptverfasser: Fujishima, Shinichiro, Okada, Yasushi, Irie, Katsumi, Kitazono, Takanari, Saku, Yoshisuke, Utsunomiya, Hidetsuna, Sugihara, Shigetaka, Sadoshima, Seizo, Fujishima, Masatoshi
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container_end_page 166
container_issue 2
container_start_page 161
container_title Angiology
container_volume 45
creator Fujishima, Shinichiro
Okada, Yasushi
Irie, Katsumi
Kitazono, Takanari
Saku, Yoshisuke
Utsunomiya, Hidetsuna
Sugihara, Shigetaka
Sadoshima, Seizo
Fujishima, Masatoshi
description A fifty-four-year-old woman died from multiple brain infarction and hemor rhage in the bilateral cerebrum, cerebellum, and brainstem, with renal infarc tion. She developed hematuria and transient blindness sixteen days before admission. Low-grade fever, heart murmur, and aortic valve vegetation on ul trasonic cardiography suggested infectious endocarditis. Autopsy study re vealed occult adenocarcinoma in the lung and nonbacterial thrombotic endocarditis, but infective endocarditis was not histologically confirmed. The patient was considered to be a rare case of nonbacterial thrombotic endocarditis who developed multiple small infarctions mainly in the brainstem and cerebel lum. Nonbacterial thrombotic endocarditis seems to be still an important dis ease as the embolic source, even if cryptic, of systemic thromboembolism.
doi_str_mv 10.1177/000331979404500213
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She developed hematuria and transient blindness sixteen days before admission. Low-grade fever, heart murmur, and aortic valve vegetation on ul trasonic cardiography suggested infectious endocarditis. Autopsy study re vealed occult adenocarcinoma in the lung and nonbacterial thrombotic endocarditis, but infective endocarditis was not histologically confirmed. The patient was considered to be a rare case of nonbacterial thrombotic endocarditis who developed multiple small infarctions mainly in the brainstem and cerebel lum. 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Nonbacterial thrombotic endocarditis seems to be still an important dis ease as the embolic source, even if cryptic, of systemic thromboembolism.</description><subject>Adenocarcinoma - complications</subject><subject>Biological and medical sciences</subject><subject>Blindness - etiology</subject><subject>Cerebral Hemorrhage - etiology</subject><subject>Cerebral Infarction - etiology</subject><subject>Coronary Thrombosis - complications</subject><subject>Coronary Thrombosis - etiology</subject><subject>Diagnosis, Differential</subject><subject>Echocardiography</subject><subject>Endocarditis - complications</subject><subject>Endocarditis - etiology</subject><subject>Female</subject><subject>Hematuria - etiology</subject><subject>Humans</subject><subject>Infarction - complications</subject><subject>Infarction - etiology</subject><subject>Kidney - blood supply</subject><subject>Lung Neoplasms - complications</subject><subject>Magnetic Resonance Imaging</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Pneumology</subject><subject>Thromboembolism - complications</subject><subject>Thromboembolism - etiology</subject><subject>Tumors of the respiratory system and mediastinum</subject><issn>0003-3197</issn><issn>1940-1574</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1994</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkUtrGzEUhUVocJ3HHwgUtCjdTaPHaDRatsZ5gNNs0vWgxx1HYUZypZlF_n1lbLwppKvL4X73XDgHoRtKvlMq5S0hhHOqpKpJLQhhlJ-hJS2qokLWn9ByD1R74jO6yPmtSEFJs0CLljJFFV-i_mkeJr8bAP9M2gf8GHqd7ORjwDo4_ABjTOlVbwGbd_wrBqPtBMnrAb-8pjiaOHmL18FFq5Pzk8-4mDxbW1zxZg5bvNLBQrpC570eMlwf5yX6fbd-WT1Um-f7x9WPTWV5rabKakNAOMmhB1abttFNa4wADkbWUjsrrTTOFEmEM6wmSjKlHCjWir7lDb9E3w6-uxT_zJCnbvTZwjDoAHHOnWy4EpyS_4KMkJYJIQrIDqBNMecEfbdLftTpvaOk27fQ_dtCOfpydJ_NCO50coy97L8e9zpbPfSphOTzCeOKt6KpC3Z7wHIpoHuLcwolvI8e_wWbU5zQ</recordid><startdate>19940201</startdate><enddate>19940201</enddate><creator>Fujishima, Shinichiro</creator><creator>Okada, Yasushi</creator><creator>Irie, Katsumi</creator><creator>Kitazono, Takanari</creator><creator>Saku, Yoshisuke</creator><creator>Utsunomiya, Hidetsuna</creator><creator>Sugihara, Shigetaka</creator><creator>Sadoshima, Seizo</creator><creator>Fujishima, Masatoshi</creator><general>SAGE Publications</general><general>Westminster</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TK</scope><scope>7X8</scope></search><sort><creationdate>19940201</creationdate><title>Multiple Brain Infarction and Hemorrhage by Nonbacterial Thrombotic Endocarditis in Occult Lung Cancer</title><author>Fujishima, Shinichiro ; Okada, Yasushi ; Irie, Katsumi ; Kitazono, Takanari ; Saku, Yoshisuke ; Utsunomiya, Hidetsuna ; Sugihara, Shigetaka ; Sadoshima, Seizo ; Fujishima, Masatoshi</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c349t-cab0e5d73efe24b86a68bb5e3eb747adc7c7bdb3eb05db24097299de9285f8363</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1994</creationdate><topic>Adenocarcinoma - complications</topic><topic>Biological and medical sciences</topic><topic>Blindness - etiology</topic><topic>Cerebral Hemorrhage - etiology</topic><topic>Cerebral Infarction - etiology</topic><topic>Coronary Thrombosis - complications</topic><topic>Coronary Thrombosis - etiology</topic><topic>Diagnosis, Differential</topic><topic>Echocardiography</topic><topic>Endocarditis - complications</topic><topic>Endocarditis - etiology</topic><topic>Female</topic><topic>Hematuria - etiology</topic><topic>Humans</topic><topic>Infarction - complications</topic><topic>Infarction - etiology</topic><topic>Kidney - blood supply</topic><topic>Lung Neoplasms - complications</topic><topic>Magnetic Resonance Imaging</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Pneumology</topic><topic>Thromboembolism - complications</topic><topic>Thromboembolism - etiology</topic><topic>Tumors of the respiratory system and mediastinum</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Fujishima, Shinichiro</creatorcontrib><creatorcontrib>Okada, Yasushi</creatorcontrib><creatorcontrib>Irie, Katsumi</creatorcontrib><creatorcontrib>Kitazono, Takanari</creatorcontrib><creatorcontrib>Saku, Yoshisuke</creatorcontrib><creatorcontrib>Utsunomiya, Hidetsuna</creatorcontrib><creatorcontrib>Sugihara, Shigetaka</creatorcontrib><creatorcontrib>Sadoshima, Seizo</creatorcontrib><creatorcontrib>Fujishima, Masatoshi</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Neurosciences Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Angiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Fujishima, Shinichiro</au><au>Okada, Yasushi</au><au>Irie, Katsumi</au><au>Kitazono, Takanari</au><au>Saku, Yoshisuke</au><au>Utsunomiya, Hidetsuna</au><au>Sugihara, Shigetaka</au><au>Sadoshima, Seizo</au><au>Fujishima, Masatoshi</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Multiple Brain Infarction and Hemorrhage by Nonbacterial Thrombotic Endocarditis in Occult Lung Cancer: A Case Report</atitle><jtitle>Angiology</jtitle><addtitle>Angiology</addtitle><date>1994-02-01</date><risdate>1994</risdate><volume>45</volume><issue>2</issue><spage>161</spage><epage>166</epage><pages>161-166</pages><issn>0003-3197</issn><eissn>1940-1574</eissn><coden>ANGIAB</coden><abstract>A fifty-four-year-old woman died from multiple brain infarction and hemor rhage in the bilateral cerebrum, cerebellum, and brainstem, with renal infarc tion. She developed hematuria and transient blindness sixteen days before admission. Low-grade fever, heart murmur, and aortic valve vegetation on ul trasonic cardiography suggested infectious endocarditis. Autopsy study re vealed occult adenocarcinoma in the lung and nonbacterial thrombotic endocarditis, but infective endocarditis was not histologically confirmed. The patient was considered to be a rare case of nonbacterial thrombotic endocarditis who developed multiple small infarctions mainly in the brainstem and cerebel lum. Nonbacterial thrombotic endocarditis seems to be still an important dis ease as the embolic source, even if cryptic, of systemic thromboembolism.</abstract><cop>Thousand Oaks, CA</cop><pub>SAGE Publications</pub><pmid>8129193</pmid><doi>10.1177/000331979404500213</doi><tpages>6</tpages></addata></record>
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subjects Adenocarcinoma - complications
Biological and medical sciences
Blindness - etiology
Cerebral Hemorrhage - etiology
Cerebral Infarction - etiology
Coronary Thrombosis - complications
Coronary Thrombosis - etiology
Diagnosis, Differential
Echocardiography
Endocarditis - complications
Endocarditis - etiology
Female
Hematuria - etiology
Humans
Infarction - complications
Infarction - etiology
Kidney - blood supply
Lung Neoplasms - complications
Magnetic Resonance Imaging
Medical sciences
Middle Aged
Pneumology
Thromboembolism - complications
Thromboembolism - etiology
Tumors of the respiratory system and mediastinum
title Multiple Brain Infarction and Hemorrhage by Nonbacterial Thrombotic Endocarditis in Occult Lung Cancer: A Case Report
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