Protection by verapamil of globally ischemic rat hearts: Energy preservation, a partial explanation

The relationship between energy preservation and the recovery of heart function was studied in globally ischemic hearts which were treated with verapamil. Isolated working rat hearts reperfused after 27 min of ischemia recovered 17.9±5.11% of pre-ischemic contractile function and had markedly reduce...

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Veröffentlicht in:	Journal of molecular and cellular cardiology 1985-01, Vol.17 (8), p.797-804
Hauptverfasser:	Watts, John A., Maiorano, Lee J., Maiorano, Peggy C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenine nucleotide Adenosine Diphosphate - metabolism Adenosine Triphosphate - metabolism Animals ATP Biological and medical sciences Ca 2+ Antagonist Cardiovascular system Coronary Disease - drug therapy Energy Metabolism Heart - drug effects Ischemia Medical sciences Miscellaneous Myocardium - metabolism Perfusion Pharmacology. Drug treatments Rats Rats, Inbred Strains Reperfusion Verapamil Verapamil - therapeutic use
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