A self-renewing, bipotential erythroid/mast cell progenitor in continuous cultures of normal murine bone marrow

We have established permanent lines of nonadherent cells from fresh normal mouse bone marrow in media containing pokeweed mitogen‐stimulated spleen cell conditioned medium (PWSCM). These lines continuously produced erythropoietic progenitor cells (detected by their ability to form erythroid bursts i...

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Veröffentlicht in:	Journal of cellular physiology 1985-10, Vol.125 (1), p.10-18
Hauptverfasser:	Wendling, Françoise, Shreeve, Mona, McLeod, David, Axelrad, Arthur
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal cells Animals Biological and medical sciences Bone Marrow Cells Cell cultures. Hybridization. Fusion Colony-Forming Units Assay Erythroblasts - cytology Female Fundamental and applied biological sciences. Psychology Hematopoietic Stem Cells - cytology Histamine - analysis Male Mast Cells - cytology Mice Mice, Inbred C57BL Microscopy, Electron Molecular and cellular biology Pokeweed Mitogens - pharmacology Receptors, Fc - metabolism Receptors, IgE Receptors, Immunologic - metabolism Spleen - cytology Time Factors
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