Expression of Prostaglandin-Endoperoxide Synthase 1 and Prostaglandin-Endoperoxide Synthase 2 in Human Osteoblasts

A Prostaglandin endoperoxide synthase isoenzyme was recently identified in several cell lines. Osteoblasts possess Prostaglandin endoperoxide synthase activity, but it is not known which isoenzymes are present in these cells. Our objective was to identify these isoenzymes in human osteoblasts. Resti...

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Veröffentlicht in:	Biochemical and biophysical research communications 1994-02, Vol.198 (3), p.955-960
Hauptverfasser:	Debrumfernandes, A.J., Laporte, S., Heroux, M., Lora, M., Patry, C., Menard, H.A., Dumais, R., Leduc, R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkaline Phosphatase - metabolism Analytical, structural and metabolic biochemistry Biological and medical sciences Blotting, Northern Cells, Cultured Cyclic AMP - metabolism Dexamethasone - pharmacology Dinoprostone - metabolism Enzymes and enzyme inhibitors Fundamental and applied biological sciences. Psychology Gene Expression - drug effects Humans Interleukin-1 - pharmacology Isoenzymes - biosynthesis Kinetics Osteoblasts - drug effects Osteoblasts - enzymology Osteoblasts - metabolism Osteocalcin - biosynthesis Oxidoreductases Prostaglandin-Endoperoxide Synthases - biosynthesis Recombinant Proteins - pharmacology RNA, Messenger - analysis RNA, Messenger - biosynthesis Tumor Necrosis Factor-alpha - pharmacology
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