An analysis of regulatory elements in the phosphoenolpyruvate carboxykinase (GTP) gene which are responsible for its tissue-specific expression and metabolic control in transgenic mice

Sequences in the gene for P-enolpyruvate carboxykinase (PEPCK) which are responsible for its complex pattern of transcriptional control were determined using transgenic mice containing a chimeric PEPCK-bovine growth hormone (bGH) gene consisting of a segment of the PEPCK promoter from -460 to +73, w...

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Veröffentlicht in:	The Journal of biological chemistry 1994-02, Vol.269 (8), p.5619-5628
Hauptverfasser:	PATEL, V. M, YUN, J. S, JINSONG LIU, MCGRANE, M. M, HANSON, R. W
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Cyclic AMP - metabolism Diet Fundamental and applied biological sciences. Psychology Gene Expression Regulation, Enzymologic Growth Hormone - genetics Liver - embryology Liver - metabolism Mice Mice, Transgenic Molecular and cellular biology Molecular genetics Mutation Phosphoenolpyruvate Carboxykinase (GTP) - genetics Phosphoenolpyruvate Carboxykinase (GTP) - metabolism Promoter Regions, Genetic Regulatory Sequences, Nucleic Acid Transcription, Genetic Transcription. Transcription factor. Splicing. Rna processing
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