Discriminative stimulus- and open-field effects of the enantiomers of 11-hydroxy-delta-8-tetrahydrocannabinol in pigeons and gerbils

The cannabimimetic activity of the two enantiomers of 11-hydroxy-delta-8-tetrahydrocannabinol (11-OH-delta-8-THC) was evaluayed in pigeons trained to discriminate between the presence and absence of (−)-delta-9-tetrahydrocannabinol [(−)-delta-9-THC]. (−)-11-OH-Delta-8-THC exhibited cannabimimetic ac...

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Veröffentlicht in:	Pharmacology, biochemistry and behavior biochemistry and behavior, 1994, Vol.47 (1), p.113-119
Hauptverfasser:	Järbe, Torbjörn U.C., Mechoulam, Raphael, Zahalka, Jamal
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Behavior, Animal - drug effects Biological and medical sciences Cannabimimetic Cannabinoids - pharmacology Columbidae Discrimination Discrimination (Psychology) - drug effects Discrimination Learning - drug effects Dose-Response Relationship, Drug Dronabinol - analogs & derivatives Dronabinol - pharmacology Drug addictions Enantiomers Gerbillinae Gerbils Male Marijuana Medical sciences Open-field Operant Pigeons Rodentia Stereoisomerism Stereoselectivity Stimulus Structure-Activity Relationship Structure-activity relationship (SAR) Tetrahydrocannabinol THC cue Toxicology
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