Vasopressin induced production of inositol trisphosphate and calcium efflux in a smooth muscle cell line

Phosphatidylinositol metabolism and 45Ca 2+ efflux were examined in a vascular smooth muscle cell line (A 7r 5). [Arg 8]Vasopressin stimulated the rapid formation (measurable at 1 sec) of inositol phosphates in a concentration-dependent manner. The time course for formation of inositol phosphates wa...

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Veröffentlicht in:	Biochem. Biophys. Res. Commun.; (United States) 1985-08, Vol.131 (1), p.469-476
Hauptverfasser:	Doyle, Valerie M., Rüegg, Urs T.
Format:	Artikel
Sprache:	eng
Schlagworte:	560171 - Radiation Effects- Nuclide Kinetics & Toxicology- Man- (-1987) ALKALINE EARTH ISOTOPES ANIMALS Applied sciences Arginine Vasopressin - analogs & derivatives Arginine Vasopressin - antagonists & inhibitors Arginine Vasopressin - pharmacology BETA DECAY RADIOISOTOPES BETA-MINUS DECAY RADIOISOTOPES BIOCHEMICAL REACTION KINETICS BIOLOGICAL EFFECTS calcium Calcium - metabolism CALCIUM 45 CALCIUM ISOTOPES Calcium Radioisotopes - metabolism CARBOHYDRATES CATIONS Cell Line CHARGED PARTICLES Chlorides - pharmacology DAYS LIVING RADIOISOTOPES EVEN-ODD NUCLEI Exact sciences and technology HORMONES INOSITOL Inositol 1,4,5-Trisphosphate Inositol Phosphates - biosynthesis INOSITOLS INTERMEDIATE MASS NUCLEI IONS ISOTOPES KINETICS Lithium - pharmacology Lithium Chloride MAMMALS MEMBRANE TRANSPORT METABOLISM MONOSACCHARIDES Muscle, Smooth, Vascular - drug effects Muscle, Smooth, Vascular - metabolism MUSCLES NUCLEI ORGANIC COMPOUNDS Other techniques and industries PEPTIDE HORMONES PITUITARY HORMONES RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT RADIOISOTOPES RATS REACTION KINETICS RODENTS SACCHARIDES smooth muscle Sugar Phosphates - biosynthesis VASOPRESSIN VERTEBRATES
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