Risk factors and the incidence of hypertension in black physicians: The Meharry Cohort Study

A prospective longitudinal study of black medical students was conducted to determine the predictive value of hypertension precursors. Follow-up examinations, averaging 22.5 years later, were performed on 341 subjects (78.8%); 25 (5.8%) additional subjects were identified as dead out of 433 original...

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Veröffentlicht in:The American heart journal 1985-09, Vol.110 (3), p.637-645
Hauptverfasser: Thomas, John, Semenya, Kofi A., Neser, William B., Thomas, D.Johniene, Green, Donald R., Gillum, Richard F.
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container_title The American heart journal
container_volume 110
creator Thomas, John
Semenya, Kofi A.
Neser, William B.
Thomas, D.Johniene
Green, Donald R.
Gillum, Richard F.
description A prospective longitudinal study of black medical students was conducted to determine the predictive value of hypertension precursors. Follow-up examinations, averaging 22.5 years later, were performed on 341 subjects (78.8%); 25 (5.8%) additional subjects were identified as dead out of 433 original participants. Results are reported on 313 reexamined men. A remarkable 43.8% of the physicians had elevated blood pressure higher than 140 90 mm Hg or gave a history of hypertension and treatment. Correlation coefficients, quintile distributions, and regressions all confirmed the ability of baseline SBP and DBP to predict their respective pressures on follow-up examination. Discriminant function tests yielded baseline SBP, DBP, smoking, and parental history of stroke or hypertension to be the most significant precursors distinguishing hypertensive from normotensive groups, and the model correctly classified 69.7% of the subjects. Baseline cholesterol and Quetelet index levels did not reach statistical significance. The cold pressor test was not predictive but interim weight gain was highly significant. Results are discussed in relation to comparable studies on white populations.
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Follow-up examinations, averaging 22.5 years later, were performed on 341 subjects (78.8%); 25 (5.8%) additional subjects were identified as dead out of 433 original participants. Results are reported on 313 reexamined men. A remarkable 43.8% of the physicians had elevated blood pressure higher than 140 90 mm Hg or gave a history of hypertension and treatment. Correlation coefficients, quintile distributions, and regressions all confirmed the ability of baseline SBP and DBP to predict their respective pressures on follow-up examination. Discriminant function tests yielded baseline SBP, DBP, smoking, and parental history of stroke or hypertension to be the most significant precursors distinguishing hypertensive from normotensive groups, and the model correctly classified 69.7% of the subjects. Baseline cholesterol and Quetelet index levels did not reach statistical significance. The cold pressor test was not predictive but interim weight gain was highly significant. 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Etiology</subject><subject>Cold Temperature</subject><subject>Exercise Test</subject><subject>Heart Rate</subject><subject>Humans</subject><subject>Hypertension - epidemiology</subject><subject>Hypertension - etiology</subject><subject>Hypertension - genetics</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Physicians</subject><subject>Prospective Studies</subject><subject>Risk</subject><subject>Students, Medical</subject><subject>Tennessee</subject><issn>0002-8703</issn><issn>1097-6744</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1985</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE1r3DAQhkVpSTdp_kELOpSSHJyOV9aHcyiUJUkDCYE2vRWELI2wGq-1kbwF__va2WWPOQ3ifeZl9BDysYSLEkrxFQCWhZLAzhQ_rwGULOANWZRQy0LIqnpLFgfkPTnO-e_0FEsljshRBUxIVS_In58hP1Fv7BBTpqZ3dGiRht4Gh71FGj1txw2mAfscYj8ltOmMfaKbdszBBtPnS_o4rdxja1Ia6Sq2MQ3017B14wfyzpsu4-l-npDf11ePqx_F3cPN7er7XWErvhyKRtRYMUShGPfSVsa6RjaKM86llwAMhLDKSmO8qJ2tReNx-ofjjkvTeGAn5Muud5Pi8xbzoNchW-w602PcZi0FE4yLcgKrHWhTzDmh15sU1iaNugQ9S9WzMT0b04rrF6l67v-07982a3SHpb3FKf-8z022pvPJTP7yAauXsq5grvm2w3By8S9g0tmG2bILCe2gXQyv3_EfNgqTUA</recordid><startdate>198509</startdate><enddate>198509</enddate><creator>Thomas, John</creator><creator>Semenya, Kofi A.</creator><creator>Neser, William B.</creator><creator>Thomas, D.Johniene</creator><creator>Green, Donald R.</creator><creator>Gillum, Richard F.</creator><general>Mosby, Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>198509</creationdate><title>Risk factors and the incidence of hypertension in black physicians: The Meharry Cohort Study</title><author>Thomas, John ; Semenya, Kofi A. ; Neser, William B. ; Thomas, D.Johniene ; Green, Donald R. ; Gillum, Richard F.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c452t-b69e43ee6835f7c4acdb7b853557f7003066c8c7aaf69dc96bfe628d5d57abf03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1985</creationdate><topic>Adult</topic><topic>African Americans</topic><topic>Arterial hypertension. 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source MEDLINE; Elsevier ScienceDirect Journals Complete
subjects Adult
African Americans
Arterial hypertension. Arterial hypotension
Biological and medical sciences
Blood and lymphatic vessels
Blood Pressure
Body Height
Body Weight
Cardiology. Vascular system
Clinical manifestations. Epidemiology. Investigative techniques. Etiology
Cold Temperature
Exercise Test
Heart Rate
Humans
Hypertension - epidemiology
Hypertension - etiology
Hypertension - genetics
Male
Medical sciences
Physicians
Prospective Studies
Risk
Students, Medical
Tennessee
title Risk factors and the incidence of hypertension in black physicians: The Meharry Cohort Study
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